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CompletedNCT03400644Updated Feb 12, 2019

Are Rigid Cervical Collars Necessary for Open-door Laminoplasty and Titanium Arch Plates for Cervical Myelopathy?

An interventional study of Cervical collar in Cervical Myelopathy, sponsored by The University of Hong Kong. Completed at 1 site in Hong Kong. Per ClinicalTrials.gov, last updated 2019-02-12.

Sponsored by The University of Hong Kong · Not applicable, Interventional, and Supportive care

Phase
Not applicable
Study type
Interventional
Enrollment
35
Allocation
Randomized
Sex
All
01

Study summary

This is a randomized controlled trial to assess the use of rigid neck collar postoperatively. It consists of patients with cervical myelopathy undergoing open-door laminoplasty with titanium arch plates. Patients are divided into two groups: one group are not using rigid neck collar whereas the second group of patients wear rigid neck collar for three weeks postoperatively. Both groups of patients will then be assessed at fixed intervals. Clinical assessments include the cervical spine range of motion, any axial neck pain and also a full neurological examination. Radiographs will be used to assess for any complications. Cervical spine alignment and relevant questionnaires will be done and recorded. These results will help to conclude whether we can avoid the use of rigid cervical collars postoperatively, in view of the associated problems arising from restricted neck movement.

Read the detailed description

Current management protocols regarding cervical laminoplasty is to provide early immobilization with rigid cervical neck collars to avoid implant failure, loss of correction and recurrence of neurological deficit. However, there is no strong evidence supporting the need for neck collars in laminoplasty especially since modern plating fixation methods are already very rigid. Cervical neck collars should also not be used haphazardly due to possible complications and cost implications. Cervical range of motion has been shown to reduce with rigid cervical collars. Decreased voluntary eye movement and postural stability has also been illustrated. Longer duration of neck collar use may even lead to postoperative axial neck pain. Neck collars has also been linked to complications such as pressure ulcers, nerve palsy, skin reactions, dysphagia and respiratory problems. The costs of collar manufacturing and maintenance is not small and must also be taken into consideration. With stronger fixation devices like plates, the above complications can be avoided. Most clinicians still use neck collars for protection mainly due to historical reasons. However this is not an evidence-based approach. By eliminating the need for neck collars, patients are allowed earlier mobilization, less neck stiffness and axial neck pain while reducing its cost. Hence this study is important to provide a basis for changing clinical practice. The study is a prospective randomized controlled trial. Patients are consecutively and randomly divided into two groups . One group of patients will receive no cervical collar postoperatively and a second group will receive rigid neck collar for 3 weeks postoperatively. Operative techniques will be standardized. All assessments are performed 3 and 6 weeks, and 3, 6, 12 and 24 months postoperatively. The subjects were analysed in terms of clinical and functional outcomes through radiographic measurements, clinical assessment and questionnaires.

02

Conditions studied

  • Cervical Myelopathy

Keywords

  • open-door laminoplasty, laminoplasty, cervical collars
03

Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients attending either Queen Mary Hospital or Duchess of Kent Children's Hospital, who are over 18 years of age, and present with clinical and radiological signs compatible with cervical myelopathy undergoing laminoplasty. Patients must be literate and able to comprehend the study to be enrolled.

Exclusion criteria

Exclusion Criteria:

  • All patients with previous cervical spine surgery, congenital deformities, spine infection or inflammation, tumour, fusion surgery, non-Chinese, undergoing workman's compensation and unable or refuse to follow the standardized rehabilitation protocol.
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Double (Care provider, Outcomes assessor)
Enrollment
35 participants (actual)

Study arms

  • Active comparator
    With Collar

    Subjects are prescribed with custom-made rigid cervical collar which are to be worn for 3 weeks postoperatively

    Device: Cervical collar

  • No intervention
    Without Collar

    Subjects do not need to wear any cervical collar postoperatively

Interventions

  • DeviceCervical collar

    Cervical neck collar which is routinely made for post-laminoplasty patients

05

What researchers measure

Primary outcomes

  1. Cervical spine range of motion (absolute values and changes from baseline, with standard deviations)

    To be measured by a single operator using a goniometer

    Time frame: 24 months

  2. Axial neck pain (absolute values and changes from baseline, with standard deviations)

    Patient is asked to rate their axial neck pain on the day of follow-up, with the VAS scale 0-10 with 0 being the least and 10 being the worst pain experienced

    Time frame: 24 months

  3. SF-36 (absolute values and changes from baseline, with standard deviations)

    As a utility score and for assessing any difference between the cervical collar versus the without cervical collar group. The physical health component and mental health component are derived from the following subscales: Physical functioning, role limitations due to physical health, role limitations due to emotional problems, vitality, mental health, social functioning, bodily pain and general health perception

    Time frame: 24 months

  4. JOA scores (absolute values and changes from baseline, with standard deviations)

    JOA consists of 6 domain scores and allow assessment as a composite scores or from individual domain: motor dysfunction in the upper and lower extremities; sensory function in the upper and lower extremities and in the trunk; and the bladder function

    Time frame: 24 months

  5. Neck Disability Index (absolute values and changes from baseline, with standard deviations)

    An outcome score in assessing how neck pain affecting subjects' daily life activities

    Time frame: 24 months

  6. Spinal canal diameters at C3, C4, C5, C6

    To measure any difference between 2 study groups at various time points

    Time frame: 24 months

Secondary outcomes

  1. Rate of recovery (in percentage)

    to be derived from the JOA scores

    Time frame: 24 months

06

Study locations

1 site
  • Queen Mary Hospital
    Hong Kong, Hong Kong
07

Registry details

Key details

Study ID
NCT03400644
Lead sponsor
The University of Hong Kong
Responsible party
Dr. Jason Pui Yin Cheung (Clinical Assistant Professor, The University of Hong Kong) — Principal investigator
First posted
Jan 17, 2018
Start date
Apr 1, 2015
Primary completion
Feb 28, 2017
Completion
Feb 28, 2018
Last update
Feb 12, 2019

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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