ClinicalTrials.gg
CompletedNCT03394469OBESARUpdated Nov 10, 2026

Sarcopenic Obesity: Estimation of Prevalence and Identification of Clinical and Biological Determinants in a Population of Adult Obese Patients

An interventional study of collection in Obesity, sponsored by University Hospital, Clermont-Ferrand. Completed at 1 site in France. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2026-11-10.

Sponsored by University Hospital, Clermont-Ferrand · Not applicable, Interventional, and Screening

Updated Nov 10, 2026Now CompletedResults publication added+3 moreGo to Updates ↓
Phase
Not applicable
Study type
Interventional
Enrollment
799
Allocation
Not applicable
Ages
18 Years to 70 Years
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 44 studies in Obesity by University Hospital, Clermont-Ferrand — 6 open to participants now, 6 under way, none of them phase 3. Obesity · University Hospital, Clermont-Ferrand.

Enrollment
3rd of 37
799 · median 40
Started
2018
with 5 others
No phase
34 of 44
6 open now
Registered
18th of 44
by date

Among the 44 studies in Obesity by University Hospital, Clermont-Ferrand, this one is the 3rd largest by enrollment of the 37 interventional ones that give a count, is one of 6 that started in 2018, is one of 34 with no phase, and was the 18th registered.

Obesity

11,522 studies on the registry are indexed under Obesity; 2,033 are open to participants now.

Browse Obesity studies →

Open to participants now

6 of the 44 studies in Obesity by University Hospital, Clermont-Ferrand are open now, in 1 country. Recruiting first, the newest first:

1 more — sign in →

By country, each count listing its studies:

All 6 open studies →

Where they have run

Who these studies take

Of the 1,336 Obesity studies recruiting now, 377 (28%) set no upper age limit and 856 (64%) stop at 75 or younger; 168 take children under 18; 491 take healthy volunteers.

This study: 18 Years to 70 Years · all sexes · no healthy volunteers.

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02

Study summary

This project aims first to determine the prevalence of sarcopenia in a population of obese people of extended age group (18-70 years). In a second step, the factors determining and / or predisposing to sarcopenic obesity will be identified as well as plasmatic and urinary biomarkers specific to this phenotype.

Read the detailed description

Collection of clinical and paraclinical data (biological and anthropometric) for evaluation of sarcopenic obesity in obese patients.

Biological collection to identify plasma, serum, genetic, urinary and faecal biomarkers associated with sarcopenic obesity

03

Conditions studied

  • Obesity

Keywords

  • Obesity
  • Sarcopenia
04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Age: 18-70 years
  • Sex: men and women
  • Patient followed in clinical nutrition benefiting from a metabolic assessment for optimization of clinical and paraclinical management
  • Patient meeting the criteria of obesity defined by > 30 kg / m²
  • Major patient with free, informed and signed consent
  • Patient covered by the social security scheme

Exclusion criteria

Exclusion Criteria:

  • Patient with cancer or severe chronic disease (renal failure, respiratory failure, liver failure)
  • Patient with neuromuscular disease
  • Patient with a total inability to walk
  • Minor patient
  • Refusal of the patient to participate in the study
  • Pregnant or lactating women
  • Patient deprived of liberty or under guardianship.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

05

Study design

Phase
Not applicable
Primary purpose
Screening
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
799 participants (actual)

Study arms

  • Other
    cohort

    Collection of clinical and paraclinical data (biological and anthropometric) for evaluation of sarcopenic obesity in obese patients.

    Other: collection

Interventions

  • Othercollection

    Blood, urinary and faecal samples

06

What researchers measure

Primary outcomes

  1. Sarcopenia

    The primary endpoint is sarcopenia (present / absent), defined using the muscle mass index (SMI) corresponding to = SM / Height², where the total muscle mass (SM) is calculated from validated equations. by Janssen et al in a population of men and women with a large age range (18-86 years) and adiposity (BMI: 16-48 kg / m integrating bio-impedancemetry data ( BIA).

    Time frame: at day 1

07

Study locations

1 site
  • CHU Clermont-Ferrand
    Clermont-Ferrand, 63003, France
08

References and documents

Publications

  • Pouget M, Pinel A, Miolanne M, Gentes E, Picard M, Martinez R, Mulliez A, Guillet C, Farigon N, Boirie Y. Improving the functional detection of sarcopenic obesity: prevalence and handgrip scoring in the OBESAR cohort. Obesity (Silver Spring). 2024 Dec;32(12):2237-2245. doi: 10.1002/oby.24157. Epub 2024 Oct 28. PubMed 39467062 ↗
09

Timeline

1 registry update since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedDate before it movedWhere the date was before it movedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Jun 2018 to primary completion in Apr 2022, 46 months.

Of 3,680 non-industry interventional studies with no phase under Obesity, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 43. This study's 46 months is above that.

Counting every sponsor, half of 3,843 studies reached it within 22 months; a quarter within 10 and three quarters within 42.

Since we started tracking on Sep 25, 2026, the dates moved once, on Nov 10, 2026: primary completion Jun 2020 → Apr 2022 and completion Jun 2020 → Apr 2022.

Earlier changes are on the record history on ClinicalTrials.gov ↗

How these figures are worked out, and which studies are left out of them.

Registered
Nov 16, 2017
First posted
Jan 9, 2018
StartActual
Jun 4, 2018
Primary completionActual
Apr 8, 2022was Jun 2020
CompletionActual
Apr 8, 2022was Jun 2020
Last update
Nov 10, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
Status
Status unknown→Completed
changed Nov 10, 2026
Primary completion
Jun 6, 2020→Apr 8, 2022 (actual)
Nov 10, 2026
Study completion
Jun 6, 2020→Apr 8, 2022 (actual)
Nov 10, 2026
Enrollment
800 (estimated)→799 (actual)
Nov 10, 2026
Publications
Results publication added: Pouget M, Pinel A, Miolanne M, Gentes E, Picard M, Martinez R, Mulliez A, Guillet C, Farigon N, Boirie Y. Improving the functional detection of sarcopenic obes… PubMed 39467062 ↗
Nov 10, 2026
Show all 1 update
  1. Nov 10, 2026
    Status unknown→Completed
    Publications Results publication added: Pouget M, Pinel A, Miolanne M, Gentes E, Picard M, Martinez R, Mulliez A, Guillet C, Farigon N, Boirie Y. Improving the functional detection of sarcopenic obes… PubMed 39467062 ↗
    Primary completion Jun 6, 2020→Apr 8, 2022 (now actual)
    Study completion Jun 6, 2020→Apr 8, 2022 (now actual)
    Enrollment 800 (estimated)→799 (actual)
    + 3 other changes: verification date, contact details and site details

From the registry record's own update history. This site started tracking changes on Sep 25, 2026; for anything earlier, see the record history on ClinicalTrials.gov ↗

10

Registry details

Key details

Study ID
NCT03394469
Responsible party
Sponsor
First posted
Jan 9, 2018
Start date
Jun 4, 2018
Primary completion
Apr 8, 2022
Completion
Apr 8, 2022
Last update
Nov 10, 2026

Study contacts

Yves BOIRIE
principal investigator · University Hospital, Clermont-Ferrand

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2022. You cannot join it, but the record below documents what was studied.

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Discussion

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