A Phase 4 interventional study of Propanolol in Hyperthyroidism, sponsored by Yaounde Central Hospital. Completed. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2018-01-08.
Sponsored by Yaounde Central Hospital · Phase 4, Interventional, and Treatment
Objective: The aim of our study was to evaluate the short term effects of Propanolol on heart rate variability in patients with hyperthyroidism.
Design: In ten patients newly diagnosed as having hyperthyroidism and naïve of all treatment specific for hyperthyroidism, we evaluated the short term effects of Propanolol on heart rate variability (HRV).
Methods: We measured heart rate variability by power spectral analysis during 2 hours of rest and during Ewing's tests before and after the administration of Propanolol 40mg/12 hours orally for 72 hours.
Objective: The aim of our study was to evaluate the short term effects of Propanolol on heart rate variability in patients with hyperthyroidism.
Design: In ten patients newly diagnosed as having hyperthyroidism and naïve of all treatment specific for hyperthyroidism, we evaluated the short term effects of Propanolol on heart rate variability (HRV).
Methods: We measured heart rate variability by power spectral analysis during 2 hours of rest and during Ewing's tests before and after the administration of Propanolol 40mg/12 hours orally for 72 hours. Other outcomes included mean heart rate, mean R-R interval during 2-hour rest.
The study questions the systematic adjunction of Propanolol early in the treatment of hyperthyroidism.
112 studies on the registry are indexed under Hyperthyroidism; 27 are open to participants now.
This study's enrollment of 10 is below the median of 60 across 61 interventional studies indexed under Hyperthyroidism.
Browse Hyperthyroidism studies →Yaounde Central Hospital is the lead sponsor of 22 studies on the registry; none are open to participants now.
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Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Contraindication
A reason a treatment, test or procedure should not be given to a particular person, such as an allergy, another illness or a medicine they take.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
72-hour propanolol before specific treatment of hyperthyroidism
Drug: Propanolol
72-hour propanolol before specific treatment of hyperthyroidism
Also known as: Avlocardyl
Heart rate variability
Sympatho vagal tone measures
Time frame: 72 hours
Heart rate
Heart rate
Time frame: 72 hours
No study locations are listed for this record.
Plan to share: Undecided — Availability to researchers making a formal request with restrictions in relation to national regulations on data sharing
This study is completed, as verified in Jan 2018. You cannot join it, but the record below documents what was studied.
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Studies of the drug tested here: Propranolol
Yaounde Central Hospital