ClinicalTrials.gg
CompletedNCT03374878Updated Sep 25, 2019

Oral Contraceptive and Strength Training

An interventional study of no oral contraceptive and training and oral contraceptive and training in Healthy, sponsored by University of Aarhus. Completed at 1 site in Denmark. Open to female participants aged 18 Years to 30 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-09-25.

Sponsored by University of Aarhus · Not applicable, Interventional, and Basic science

Phase
Not applicable
Study type
Interventional
Enrollment
38
Allocation
Non-randomized
Ages
18 Years to 30 Years
Sex
Female
01

Where this study stands

Counted across the records on this site · 2026-11-12

Among 30 studies in Motor Activity by University of Aarhus — 9 open to participants now, 9 under way, none of them phase 3. Motor Activity · University of Aarhus.

Enrollment
19th of 27
38 · median 60
Started
2018
with 2 others
No phase
24 of 30
9 open now
Registered
15th of 30
by date

Among the 30 studies in Motor Activity by University of Aarhus, this one is the 19th largest by enrollment of the 27 interventional ones that give a count, is one of 3 that started in 2018, is one of 24 with no phase, and was the 15th registered.

Motor Activity

9,798 studies on the registry are indexed under Motor Activity; 1,910 are open to participants now.

Browse Motor Activity studies →

Open to participants now

9 of the 30 studies in Motor Activity by University of Aarhus are open now, in 1 country. Recruiting first, the newest first:

4 more — sign in →

By country, each count listing its studies:

All 9 open studies →

Where they have run

Who these studies take

Of the 1,201 Motor Activity studies recruiting now, 517 (43%) set no upper age limit and 535 (45%) stop at 75 or younger; 180 take children under 18; 420 take healthy volunteers.

This study: 18 Years to 30 Years · female · healthy volunteers too.

The full table on the hub →

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02

Study summary

Cross sectional study investigating the effect of strength training in users and non-users of oral contraceptives (OC) (2nd generation OC)

03

Conditions studied

  • Healthy

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Keywords

  • exercise
  • oral contraceptive
  • strength training
04

Who can participate

Ages eligible
18 Years to 30 Years
Sexes eligible
Female
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • 18.5 - 30 years
  • \< 30

Exclusion criteria

Exclusion Criteria:

  • Medicine influencing protein turnover
  • Surgery on the knee
  • Arthritis
  • Diabetes
  • Smoking
  • irregular menstruation (\<24 days or >35 days cycles)
  • Non-users: not have used for the last 3 months.
  • Unstable weight (+/- 5 kg within the last 6 months)
  • Regular training/exercise more than 2 hours/week for the last 6 months. Maximum 70 km of cycling transport/week.
  • Strength training >1time/month for the last 6 months.
  • Pregnancy
  • Diet og eating disorder
  • Can not read or understand danish
Terms in these criteria, in plain language(2)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

BMI (body mass index)

Weight in kilograms divided by height in metres squared. Example: 70 kg and 1.75 m gives 70 ÷ (1.75 × 1.75) ≈ 22.9.

What counts as overweight or obesity differs between countries (some use lower cut-offs), so go by the range the study states.

Contraception

Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.

Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.

05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
38 participants (actual)

Study arms

  • Experimental
    oral contraceptive and training

    Users of oral contraceptive training for 10 weeks

    Other: oral contraceptive and training

  • Placebo comparator
    no oral contraceptive and training

    Non-users of oral contraceptive training for 10 weeks

    Other: no oral contraceptive and training

Interventions

  • Otherno oral contraceptive and training

    10 weeks of training in a group of oral contraceptive users

  • Otheroral contraceptive and training

    10 weeks of training in a group of users of oral contraceptives

06

What researchers measure

Primary outcomes

  1. Muscle mass

    Change in muscle mass determined by MRI scan of thigh muscle

    Time frame: Baseline + after 10 weeks of resistance training.

Secondary outcomes

  1. Muscle fiber size

    Change in muscle fiber cross sectional area measured by histology.

    Time frame: Baseline + after 10 weeks of resistance training.

  2. Muscle strength

    Change in isometric strength

    Time frame: Baseline + after 10 weeks of resistance training.

  3. Blood values

    Change in sex hormone profile measured by blood sample analysis

    Time frame: Baseline + after 10 weeks of resistance training.

  4. Functionality

    Change in jump performance by RSI (Reactive strength index) measures

    Time frame: Baseline + after 10 weeks of resistance training.

  5. Fat free mass (FFM)

    Change in FFM measured by dual energy x-ray absorptiometry (DXA) scan of whole body composition

    Time frame: Baseline + after 10 weeks of resistance training.

07

Study locations

1 site
  • Aarhus University, Department for Public Health, Section for Sport Science
    Aarhus, 8000, Denmark
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Ran from Feb 2018 to primary completion in Jan 2019, 11 months.

Of 5,147 non-industry interventional studies with no phase under Motor Activity, half reached primary completion within 17 months of starting (the median), counting those still running; a quarter within 7 and three quarters within 36. This study's 11 months is below that.

Counting every sponsor, half of 5,207 studies reached it within 17 months; a quarter within 7 and three quarters within 36.

How these figures are worked out, and which studies are left out of them.

Registered
Dec 5, 2017
First posted
Dec 15, 2017
StartActual
Feb 1, 2018
Primary completionActual
Jan 1, 2019
CompletionActual
Jan 1, 2019
Last update
Sep 25, 2019
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 25, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03374878
Responsible party
Mette Hansen (Associate Professor, University of Aarhus) — Principal investigator
First posted
Dec 15, 2017
Start date
Feb 1, 2018
Primary completion
Jan 1, 2019
Completion
Jan 1, 2019
Last update
Sep 25, 2019

Study contacts

Mette Hansen, PhD
principal investigator · University of Aarhus

Oversight

Data monitoring committee
Yes
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Jun 2018. You cannot join it, but the record below documents what was studied.

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Discussion

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