An interventional study of Brain Gym Exercises and Standard exercise program for institutionalized older adults. in Cognition Disorders in Old Age and Physical Activity, sponsored by University of Vigo. Completed at 1 site in Spain. Open to participants aged 65 Years and older. Per ClinicalTrials.gov, last updated 2017-12-11.
Sponsored by University of Vigo · Not applicable, Interventional, and Treatment
Among 13 studies in Cognition Disorders with a site in Spain — none open to participants now, 2 under way, none of them phase 3. Cognition Disorders · Spain.
Among the 13 studies in Cognition Disorders with a site in Spain, this one is the 6th largest by enrollment of the 10 interventional ones that give a count, is one of 2 that started in 2014, is one of 5 with no phase, and was the 8th registered.
399 studies on the registry are indexed under Cognition Disorders; 74 are open to participants now.
Browse Cognition Disorders studies →None of the 13 studies in Cognition Disorders with a site in Spain is open now.
Of the 47 Cognition Disorders studies recruiting now, 20 (43%) set no upper age limit and 12 (26%) stop at 75 or younger; 6 take children under 18; 13 take healthy volunteers.
This study: 65 Years and older · all sexes · no healthy volunteers.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
13 studies; the count open now beside each. This study's row is marked.
First in 2011; this study’s year is marked. 2 started in 2014.
This study's enrollment of 50 is below the median of 66 across 272 interventional studies indexed under Cognition Disorders.
Median enrollment 65 across the 10 interventional studies, 126 across the 3 observational. Of the 8 that completed or were terminated, 0 (0%) have results posted.
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3 of 13 have an industry lead sponsor. The 10 most frequent:
University of Vigo is the lead sponsor of 53 studies on the registry; 13 are open to participants now.
University of Vigo has 1 study filed under Cognition Disorders — fewer than ten, so there is no comparison to draw.
1 of the studies in Cognition Disorders with a site in Spain that are under way reach primary completion within a year, 0 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT03507257Indiana UniversityLongitudinal Early-onset Alzheimer's Disease Study Protocol | 2027-01-01 |
Among the 13 studies in Cognition Disorders with a site in Spain, from their registry updates:
Nothing recorded among them since 2026-09-25.
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Scientific evidence regarding the effects of Brain Gym®, on people with cognitive impairment is scarce. This study aimed at comparing the effects of a program based on Brain Gym® exercises against a fitness exercise program on the cognitive function, functional independence, physical fitness and quality of life in institutionalized older adults with cognitive impairment.
Cognitive training and physical exercise have been regarded as useful strategies in order to improve the cognitive function in older people with cognitive impairment. In this regard, it has been argued that while physical exercise improves the metabolic activity of the brain, the performance of cognitively demanding tasks increases the amount of dendritic branches and the level of synaptic plasticity, implying that the combination of both therapies may result in synergistic effects that positively influence various cognitive domains in different ways. One of the best known therapies which combines mental and physical training is Brain Gym® (BG), a movement-based program originally designed to improve learning capabilities through the performance of mind-body exercises. Brain Gym® can be considered as an interesting field of research due to the need of identifying novel therapies which might be more pleasant for older adults who tend not to be prone to participating in conventional exercise programs and might have a positive effect on their cognitive function. In spite of this, scientific evidence regarding the effects of BG on people with cognitive impairment is scarce and none of the studies compared the potential benefits of BG versus traditional exercise programs for this population. Moreover, to the authors' knowledge no study of this kind has been published so far. Under these circumstances, the present study aims at identifying the potential benefits of performing BG exercises on the cognitive function, functional independence, physical fitness, and quality of life of institutionalized older people with cognitive impairment, as well as at finding out whether the effects are more significant than those produced by a traditional exercise program.
399 studies on the registry are indexed under Cognition Disorders; 74 are open to participants now.
This study's enrollment of 50 is below the median of 66 across 272 interventional studies indexed under Cognition Disorders.
Browse Cognition Disorders studies →University of Vigo is the lead sponsor of 53 studies on the registry; 13 are open to participants now.
Compared within Cognition Disorders, this study's primary condition as ClinicalTrials.gg classifies it; the registry's first condition term is Motor Activity. The counts are of registry records indexed under each term, refreshed daily. How we classify →
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
MMSE and MoCA
Short tests of memory and thinking, each scored out of 30. Lower scores suggest more difficulty; criteria give a range, either to include people with memory problems or to leave them out.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Brain Gym® (BG) is a movement-based program originally designed to improve learning capabilities through the performance of mind-body exercises. BG can be considered as an interesting field of research due to the need of identifying novel therapies which might be more pleasant for older adults who tend not to be prone to participating in conventional exercise programs and might have a positive effect on their cognitive function. In spite of this, scientific evidence regarding the effects of BG on people with cognitive impairment is scarce.
Behavioral: Brain Gym Exercises
A traditional physical exercise program designed for institutionalized elderly people aimed at increasing their range of mobility and coordination, specifically focused on the lower limbs.
Behavioral: Standard exercise program for institutionalized older adults.
Participants in the BrainGym Exercises group performed six of the following BG exercises in every training session they took part in: "Cross Crawl", "Gravity Glider", "Arm Activation", "Belly Breathing", "Hook-ups", "Think of an X", "Lazy Eights", "Elephant", "Space Buttons", "The Owl", "Energy Yawn", "Balance Buttons" and "The Energizer". All exercises were executed from a sitting position but following the main tenets of the Brain Gym® work routine.
Participants in the Standard Exercise group took part in a traditional physical exercise program designed for institutionalized elderly people aimed at increasing their range of mobility and coordination, specifically focused on the lower limbs.
Assessment of the changes in participants' cognitive function.
By means of the Spanish version of the Mini-Mental State Examination. This is a 30-point questionnaire comprised by eight different categories and score range: Orientation to time (0-5 points) Orientation to place (0-5 points) Registration (0-3 points) Attention and calculation (0-5 points) Recall (0-3 points) Language (0-2 points) Repetition (0-1 points) Complex commands (0-6 points) The total score is the result of the summation of the categories. Interpretation: Any score greater than or equal to 24 points (out of 30) indicates a normal cognition. ≤9 points: severe cognitive impairment 10-18 points: moderate cognitive impairment 19-23 points: mild cognitive impairment
Time frame: 10 weeks
Assessment of the changes in participants' functional independence.
By means of the Barthel Index (BI) Spanish version. This scale evaluates the independence for the activities of daily living. It contains 10 different activities, with a possible score ranging from 0 to 10, with a maximum total score of the scale of 100 (summing the subscales results). Interpretation: \<20 Total dependence 21 - 60 Severe dependence 61 - 90 Moderate dependence 91 - 99 Mild dependence 100 Total Independence
Time frame: 10 weeks
Assessment of the changes in participants' health-related self-perceived quality of life.
By means of the 12-Item Short-Form Health Survey (SF-12), spanish version. For each of the 8 subscales, the value can go from 0 to 100. For the interpretation of the results, the 50 (standard deviation 10) value on each dimension must be the mean valor for the sub scale reported for the general population, meaning that more or less than 50 must be considered better or worse, respectively.
Time frame: 10 weeks
Assessment of the changes in participants' fitness level.
By means of the 5-Chair Stands Test.
Time frame: 10 weeks
Ran from Sep 2014 to primary completion in Mar 2015, 6 months.
Of 87 non-industry interventional studies with no phase under Cognition Disorders, half reached primary completion within 34 months of starting (the median), counting those still running; a quarter within 16 and three quarters within 55. This study's 6 months is below that.
Counting every sponsor, half of 92 studies reached it within 34 months; a quarter within 15 and three quarters within 55.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Dec 2017. You cannot join it, but the record below documents what was studied.
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University of Vigo