A Phase 2 interventional study of Dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 ppm fluoride). and Dentifrice containing 0.454% w/w SnF2 (1100 ppm fluoride). in Dentin Sensitivity, sponsored by GlaxoSmithKline. Withdrawn. Open to participants aged 18 Years to 65 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2019-02-15.
Sponsored by GlaxoSmithKline · Phase 2, Interventional, and Treatment
Help build ClinicalTrials.gg — short surveys, remote interviews or testing, in your language. Take part →
Among 28 studies in Dentin Sensitivity by GlaxoSmithKline — none open to participants now, none under way, none of them phase 3. Dentin Sensitivity · GlaxoSmithKline.
Among the 28 studies in Dentin Sensitivity by GlaxoSmithKline, this one is the 28th largest by enrollment, is the only one that started in 2018, is one of 6 in phase 2, and was the 27th registered.
288 studies on the registry are indexed under Dentin Sensitivity; 46 are open to participants now.
Browse Dentin Sensitivity studies →None of the 28 studies in Dentin Sensitivity by GlaxoSmithKline is open now. The open studies under Dentin Sensitivity, anywhere →
Of the 18 Dentin Sensitivity studies recruiting now, 6 (33%) set no upper age limit and 11 (61%) stop at 75 or younger; 1 takes children under 18; 11 take healthy volunteers.
This study: 18 Years to 65 Years · all sexes · healthy volunteers too.
The full table on the hub →This tab as a report to print or save as PDF → With an account.
28 studies; the count open now beside each. This study's row is marked.
First in 2008; this study’s year is marked. 1 started in 2018.
Median enrollment 164 across the 28 interventional studies. Of the 27 that completed or were terminated, 27 (100%) have results posted.
This tab as a report to print or save as PDF → With an account.
GlaxoSmithKline is the lead sponsor of 3,650 studies on the registry; 117 are open to participants now.
Of its 265 completed or terminated interventional studies of FDA-regulated products, 241 (91%) have results posted.
None of the studies under way reaches primary completion within a year.
Among the 28 studies in Dentin Sensitivity by GlaxoSmithKline, from their registry updates:
Nothing recorded among them since 2026-09-25.
This tab as a report to print or save as PDF → With an account.
The aim of this study is to develop the clinical methodology to characterize the efficacy profiles of an experimental 5% potassium nitrate (KNO3) and 0.454% stannous fluoride (SnF2) combination dentifrice and a marketed desensitizing 0.454% SnF2 only dentifrice for the relief of dentin hypersensitivity (DH), at multiple time points, over an 8 week treatment period.
This will be a single center, 8 week, randomized, controlled, examiner blind, two treatment arm, parallel design, stratified (by maximum baseline Schiff sensitivity score of the two selected test teeth), method development study, in participants in good general health, with pre-existing self-reported tooth sensitivity, and at least two sensitive teeth (diagnosed clinically) that meet all study criteria at the screening and baseline (pre-treatment) visits.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).
A drug or device being studied in a clinical trial.
It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Clinically significant
Judged by the study doctor to matter for your health or for the study. It is a doctor’s decision, so ask the study team if you are unsure whether something counts.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Childbearing potential
Able to become pregnant: from the first period until menopause, unless permanently unable to through surgery (removal of the womb, or of both ovaries or both fallopian tubes).
Criteria for people of childbearing potential usually ask for a negative pregnancy test and for contraception during the study and for a time after it.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Contraception
Ways of preventing pregnancy. “Highly effective” methods fail less than 1% of the time a year when used correctly — for example an IUD or an implant.
Criteria usually say which methods count and how long to keep using them after the last dose, sometimes for male participants too. Some studies accept a partner’s vasectomy if it was confirmed successful and that person is the participant’s only sexual partner.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Postmenopausal
Periods have stopped for good: usually no period for 12 months in a row without another medical reason, sometimes confirmed by a blood test (FSH).
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Investigational drug or device
A drug or device being studied in a clinical trial.
It may be new, or already approved and being studied for another use, dose or form. Criteria often leave out people who took part in another study of one within a recent period, commonly 30 days or five half-lives.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Hypersensitivity
An allergy, or another reaction of the immune system, to a substance. “Hypersensitivity to the study drug” means a known allergic reaction to it — not every side effect a medicine can have.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Participants in this arm will receive experimental dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 parts per million \[ppm\] fluoride).
Drug: Dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 ppm fluoride).
Participants in this arm will receive comparator dentifrice containing 0.454% SnF2 (1100ppm fluoride).
Drug: Dentifrice containing 0.454% w/w SnF2 (1100 ppm fluoride).
Participants will be instructed to dose the toothbrush with a strip of dentifrice containing 5% w/w KNO3 and 0.454% w/w SnF2 (1100 ppm fluoride) (a full brush head) and brush for at least 1 timed minute, twice daily (morning and evening), making sure to brush all sensitive areas of their teeth. Participants will be permitted to rinse with tap water post-brushing if they wish to.
Participants will be instructed to dose the toothbrush with a strip of dentifrice containing 0.454% w/w SnF2 (1100 ppm fluoride) (a full brush head) and brush for at least 1 timed minute, twice daily (morning and evening), making sure to brush all sensitive areas of their teeth. Participants will be permitted to rinse with tap water post-brushing if they wish to.
Mean Schiff Sensitivity Score at Baseline (Day 0)
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. Lesser the Schiff sensitivity score, lesser is the sensitivity of the tooth. Mean score will be calculated as the average score of the selected two test teeth at baseline.
Time frame: Baseline (Day 0)
Mean Schiff Sensitivity Score at Day 3
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. Lesser the Schiff sensitivity score, lesser is the sensitivity of the tooth. Mean score will be calculated as the average score of the two test teeth on Day 3.
Time frame: Day 3
Mean Schiff Sensitivity Score at Day 7
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. Lesser the Schiff sensitivity score, lesser is the sensitivity of the tooth. Mean score will be calculated as the average score of the two test teeth on Day 7.
Time frame: Day 7
Mean Schiff Sensitivity Score at Day 14
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. Lesser the Schiff sensitivity score, lesser is the sensitivity of the tooth. Mean score will be calculated as the average score of the two test teeth on Day 14.
Time frame: Day 14
Mean Schiff Sensitivity Score at Day 28
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. Lesser the Schiff sensitivity score, lesser is the sensitivity of the tooth. Mean score will be calculated as the average score of the two test teeth on Day 28.
Time frame: Day 28
Mean Schiff Sensitivity Score at Day 56
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. Lesser the Schiff sensitivity score, lesser is the sensitivity of the tooth. Mean score will be calculated as the average score of the two test teeth on Day 56.
Time frame: Day 56
Mean Tactile Threshold at Baseline (Day 0)
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g. Mean score will be calculated as the average score of the two test teeth on Baseline (Day 0).
Time frame: Baseline (Day 0)
Mean Tactile Threshold at Day 3
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g. Mean score will be calculated as the average score of the two test teeth on Day 3.
Time frame: Day 3
Mean Tactile Threshold at Day 7
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g. Mean score will be calculated as the average score of the two test teeth on Day 7.
Time frame: Day 7
Mean Tactile Threshold at Day 14
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g. Mean score will be calculated as the average score of the two test teeth on Day 14.
Time frame: Day 14
Mean Tactile Threshold at Day 28
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g. Mean score will be calculated as the average score of the two test teeth on Day 28.
Time frame: Day 28
Mean Tactile Threshold at Day 56
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g. Mean score will be calculated as the average score of the two test teeth on Day 56.
Time frame: Day 56
Change From Baseline (Day 0) in Schiff Sensitivity Score on Day 3
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. A reduction in Schiff Sensitivity score will indicate the improvement in sensitivity.
Time frame: Baseline (Day 0), Day 3
Change From Baseline (Day 0) in Schiff Sensitivity Score on Day 7
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. A reduction in Schiff Sensitivity score will indicate the improvement in sensitivity.
Time frame: Baseline (Day 0), Day 7
Change From Baseline (Day 0) in Schiff Sensitivity Score on Day 14
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. A reduction in Schiff Sensitivity score will indicate the improvement in sensitivity.
Time frame: Baseline (Day 0), Day 14
Change From Baseline (Day 0) in Schiff Sensitivity Score on Day 28
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. A reduction in Schiff Sensitivity score will indicate the improvement in sensitivity.
Time frame: Baseline (Day 0), Day 28
Change From Baseline (Day 0) in Schiff Sensitivity Score on Day 56
The examiner will assess the participant's response to an evaporative air stimulus for each tooth using the Schiff Sensitivity Scale scored as follows - 0: Participant does not respond to air stimulation; 1: responds to air stimulus but does not request discontinuation of stimulus; 2: Participant responds to air stimulus and requests discontinuation or moves from stimulus; 3: Participant responds to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus. A reduction in Schiff Sensitivity score will indicate the improvement in sensitivity.
Time frame: Baseline (Day 0), Day 56
Change From Baseline (Day 0) in Tactile Threshold on Day 3
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g.
Time frame: Baseline (Day 0), Day 3
Change From Baseline (Day 0) in Tactile Threshold on Day 7
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g.
Time frame: Baseline (Day 0), Day 7
Change From Baseline (Day 0) in Tactile Threshold on Day 14
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g.
Time frame: Baseline (Day 0), Day 14
Change From Baseline (Day 0) in Tactile Threshold on Day 28
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g.
Time frame: Baseline (Day 0), Day 28
Change From Baseline (Day 0) in Tactile Threshold on Day 56
The examiner will assess the response to tactile sensitivity using a Yeaple probe which will allow application of a known force to the dentin surface, starting at 10g and rising in increments of 10g until the tactile threshold or maximum force will reach. The tactile threshold for each tooth will be determined by asking the participants whether the sensation caused discomfort. The pressure setting at which the participant will give two consecutive 'yes' responses will be recorded as the tactile threshold. Higher tactile threshold will indicate the less sensitive are the tooth. At baseline, the maximum force will be 20g; at all subsequent visits, it will be 80g. However, in situations where participants will not give a 'yes' response at force of 80g, the tactile threshold will be recorded as \>80g.
Time frame: Baseline (Day 0), Day 56
Number of sensitive teeth (Schiff sensitivity score ≥ 1) on Day 0 (Baseline)
The number of teeth with a Schiff sensitivity score of ≥1 will be consider sensitive teeth. Schiff sensitivity scores were as follows:0= Subject does not respond to air stimulation, 1= if participants respond to air stimulus but does not request discontinuation of stimulus; 2= participants respond to air stimulus and requests discontinuation or moves from stimulus; 3 = participants respond to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus.
Time frame: Baseline (Day 0)
Number of sensitive teeth (Schiff sensitivity score ≥ 1) on Day 3
The number of teeth with a Schiff sensitivity score of ≥1 will be consider sensitive teeth. Schiff sensitivity scores were as follows:0= Subject does not respond to air stimulation, 1= if participants respond to air stimulus but does not request discontinuation of stimulus; 2= participants respond to air stimulus and requests discontinuation or moves from stimulus; 3 = participants respond to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus.
Time frame: Day 3
Number of sensitive teeth (Schiff sensitivity score ≥ 1) on Day 7
The number of teeth with a Schiff sensitivity score of ≥1 will be consider sensitive teeth. Schiff sensitivity scores were as follows:0= Subject does not respond to air stimulation, 1= if participants respond to air stimulus but does not request discontinuation of stimulus; 2= participants respond to air stimulus and requests discontinuation or moves from stimulus; 3 = participants respond to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus.
Time frame: Day 7
Number of sensitive teeth (Schiff sensitivity score ≥ 1) on Day 14
The number of teeth with a Schiff sensitivity score of ≥1 will be consider sensitive teeth. Schiff sensitivity scores were as follows:0= Subject does not respond to air stimulation, 1= if participants respond to air stimulus but does not request discontinuation of stimulus; 2= participants respond to air stimulus and requests discontinuation or moves from stimulus; 3 = participants respond to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus.
Time frame: Day 14
Number of sensitive teeth (Schiff sensitivity score ≥ 1) on Day 28
The number of teeth with a Schiff sensitivity score of ≥1 will be consider sensitive teeth. Schiff sensitivity scores were as follows:0= Subject does not respond to air stimulation, 1= if participants respond to air stimulus but does not request discontinuation of stimulus; 2= participants respond to air stimulus and requests discontinuation or moves from stimulus; 3 = participants respond to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus.
Time frame: Day 28
Number of sensitive teeth (Schiff sensitivity score ≥ 1) on Day 56
The number of teeth with a Schiff sensitivity score of ≥1 will be consider sensitive teeth. Schiff sensitivity scores were as follows:0= Subject does not respond to air stimulation, 1= if participants respond to air stimulus but does not request discontinuation of stimulus; 2= participants respond to air stimulus and requests discontinuation or moves from stimulus; 3 = participants respond to stimulus, considers stimulus to be painful, and requests discontinuation of the stimulus.
Time frame: Day 56
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
Start is estimated for Oct 2018; primary completion for Dec 2018, 2 months later.
How these figures are worked out, and which studies are left out of them.
This study is withdrawn, as verified in Feb 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.