An interventional study of Cardiac MRI and Applanation tonometry in Stiffness, Aortic, Cardiac Remodeling, Ventricular and Vascular Remodeling, sponsored by Central Hospital, Nancy, France. Completed at 1 site in France. Open to male participants aged 18 Years to 39 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-02-11.
Sponsored by Central Hospital, Nancy, France · Not applicable, Interventional, and Basic science
Regular sustained physical activity creates a cardiac remodelling : it is athlete's heart. In our preliminary work published in 2016, the investigators demonstrated in a small population of triathletes that there is also a vascular remodelling named athlete's artery. Moreover, the investigators know that left ventricle and aorta behave together like a couple. So they want to study by Cardiovascular Magnetic Resonance Imaging the impact of triathlon on the cardiac AND aortic remodelling.
to have carried out a clinical screening adapted to the research
*** Triathlete group:
to have a defined training volume: less than 8 hours per week during the winter months and between 10 and 15 hours per week in preparation of the objective
***Control group:
Exclusion Criteria:
Every triathlete will realize three cardiac MRI exams.The second of those will be done at the fitness peak, 2-3 weeks before the main objective of the sports season. Training will be increased between the study beginning and the first MRI, and the second exam. After each cardiac MRI, an applanation tonometry examination will aslo be performed.
Device: Cardiac MRI · Device: Applanation tonometry
Every control subject will also realize three cardiac MRI exams if possible at the same time as the triathletes.They must be not engaged in physical activity more than 150 minutes a week on average. After each cardiac MRI, an applanation tonometry examination will aslo be performed.
Device: Cardiac MRI · Device: Applanation tonometry
Non injected cardiac MRI exam
Applanation tonometry and ECG
Aortic compliance in triathletes in mm2/mmHG
aortic compliance = pulsed pressure-to-absolute variation of aortic surface ratio
Time frame: at baseline, at the fitness peak (6 to 10 months later) and at recovery (3 to 6 months after the fitness peak)
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Vascular Remodeling
Central Hospital, Nancy, France