An observational study in Vitamin D Deficiency, Obesity and Diabetes Mellitus, sponsored by Bispebjerg Hospital. Completed at 1 site in Denmark. Per ClinicalTrials.gov, last updated 2017-11-06.
Sponsored by Bispebjerg Hospital · Observational
Among 17 studies in Vitamin D Deficiency with a site in Denmark — none open to participants now, none under way, none of them phase 3. Vitamin D Deficiency · Denmark.
Among the 17 studies in Vitamin D Deficiency with a site in Denmark, this one is one of 2 that started in 2012, is one of 2 observational ones, and was the 15th registered.
801 studies on the registry are indexed under Vitamin D Deficiency; 60 are open to participants now.
This study's enrollment of 222,776 is above the median of 138 across 185 observational studies indexed under Vitamin D Deficiency.
Browse Vitamin D Deficiency studies →None of the 17 studies in Vitamin D Deficiency with a site in Denmark is open now.
Of the 37 Vitamin D Deficiency studies recruiting now, 16 (43%) set no upper age limit and 18 (49%) stop at 75 or younger; 10 take children under 18; 11 take healthy volunteers.
This study: all sexes.
The full table on the hub →17 studies; the count open now beside each. This study's row is marked.
First in 2001; this study’s year is marked. 2 started in 2012.
Median enrollment 102 across the 15 interventional studies, 111,612 across the 2 observational. Of the 14 that completed or were terminated, 2 (14%) have results posted.
None of the 17 has an industry lead sponsor. The 8 most frequent:
Bispebjerg Hospital is the lead sponsor of 289 studies on the registry; 29 are open to participants now.
Bispebjerg Hospital has 2 studies filed under Vitamin D Deficiency — fewer than ten, so there is no comparison to draw.
None of the studies under way reaches primary completion within a year.
Among the 17 studies in Vitamin D Deficiency with a site in Denmark, from their registry updates:
Nothing recorded among them since 2026-09-25.
Vitamin D deficiency is common among otherwise healthy pregnant women and may have consequences for them as well as the early development and long-term health of their children. However, the importance of maternal vitamin D status has not been widely studied.
The present study is divided into a societal experiment (1) and a case-cohort study (2):
The present study includes an in-depth examination of the influence of exposure to vitamin D early in life and during critical periods of growth for development of type 1 diabetes (T1D), type 2 diabetes, gestational diabetes, pre-eclampsia, obesity, asthma, arthritis, cancer, mental and cognitive disorders, congenital disorders, dental caries and bone fractures during child- and adulthood. The study is based on the fact that mandatory fortification of margarine with vitamin D, which initiated in 1937, was terminated in 1985.
Apart from determining the influences of exposure prior to conception and during pre- and postnatal life, the investigators examined the importance of vitamin D exposure during specific seasons and trimesters, by comparing disease incidence among individuals born before and after the fortification.
Unparalleled, the study will help determine the effects of vitamin D exposure during critical periods in life. There are a sufficient number of individuals to verify any effects during different gestation phases and seasons of the year. The results, which will change our current understanding of the significance of vitamin D, will enable new research in related fields, including interventional research designed to assess supplementation needs for different subgroups of pregnant women. Also, other health outcomes can subsequently be studied to generate multiple new interdisciplinary health research opportunities involving vitamin D.
Entire Danish population born between June1983-May1985 and September 1986-August 1988.
For the part of the study using vitamin D measurements from DBS:
The Danish Civil registration system was used to identify all live-born children during 1981-2002 (n = 1,360,466), and a random subcohort thereof was sampled for 25(OH)D analyses to be used across the D-tect studies (n = 3585)
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
1.Born outside Denmark
1. Individuals born between June1983 and May1985 were exposed to the mandatory vitamin D margarine fortification during fetal life. 2. Cases: individuals defined as having one of the aforementioned diseases of interest from the registers
Other: D-tect
1. Individuals born between September1986 and August 1988 were not exposed to the mandatory vitamin D margarine fortification during fetal life. 2. Controls: cohort of matched disease-free individuals
Other: D-tect
1. This study is based on a unique Danish social experiment that took place during a well-defined period between 1937 and December 1985, when it was mandatory to fortify all margarine with vitamin D (1.25 μg/100 g). This well-defined vitamin D fortification period makes it possible to investigate the impact of fetal exposure to extra vitamin D from food fortification on the risk of developing diseases later on. This study is possible due not only to the well-defined adjacent time window but also to the complete registration of every citizen via a civil registration number. This number can be linked, on an individual level, to Danish birth, patient and medical registries; social and ethnic registries; and clinical and other large databases 2. Case-cohort study: vitamin D measurements from dried blood spots and the risk of diseases later on
Obesity
Register based
Time frame: 2012-2025
Type 1 diabetes
Register based
Time frame: 2012-2016
Pre-eclampsia
Register based
Time frame: 2012-2025
Bone facture
Register based
Time frame: 2012-2025
Type 2 diabetes
Register based
Time frame: 2014-2025
Gestational diabetes
Register based
Time frame: 2014-2025
Asthma
Register based
Time frame: 2015-2025
Arthritis
Register based
Time frame: 2018-2025
Birth weight
Register based
Time frame: 2014-2019
Mental diseases
Register based
Time frame: 2012-2025
Cancers
Register based
Time frame: 2018-2025
Mental disorders
Register based
Time frame: 2018-2025
Dental caries
Register based
Time frame: 2018-2025
Congenital disorders
Register based
Time frame: 2018-2025
Plan to share: No
Ran from Apr 2012 to primary completion in Sep 2016, 53 months.
Of 61 non-industry observational studies under Vitamin D Deficiency, half reached primary completion within 19 months of starting (the median), counting those still running; a quarter within 9 and three quarters within 40. This study's 53 months is above that.
Counting every sponsor, half of 62 studies reached it within 19 months; a quarter within 9 and three quarters within 40.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.
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