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TerminatedNCT03319407Updated Apr 12, 2023Results posted

EPAD Monitoring of Patients Undergoing Robotic Assisted Laparoscopic Genitourinary Surgery

An interventional study of EPAD monitoring system in Surgery, sponsored by Mayo Clinic. Terminated at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2023-04-12.

Sponsored by Mayo Clinic · Not applicable, Interventional, and Supportive care

Why this study was terminated
Funding support unavailable
Phase
Not applicable
Study type
Interventional
Enrollment
21
Allocation
Not applicable
Ages
18 Years and older
Sex
All
01

Study summary

Participants to be enrolled in this study will have been scheduled to have laparoscopic genitourinary surgery and EPAD monitoring as part of their clinical care intraoperatively. Patients scheduled for genitourinary surgery are often at risk for developing nerve injuries due to intraoperative positioning.

Somatosensory evoked potential devices (SSEP) are commonly used to detect pending injury to peripheral nerves. The purpose of the present study is to use SSEP monitoring to determine the incidence and potential causes of significant changes in SSEP waveforms and correlate these changes with neurologic status of the brachial plexus after robotic surgery.

02

Conditions studied

  • Surgery
03

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients scheduled to undergo robotic assisted laparoscopic genitourinary surgery
  • Patients who are scheduled to have EPAD monitoring as part of their clinical care intraoperatively

Exclusion criteria

Exclusion Criteria:

  • Patients with previous history of polyneuropathy, carpal tunnel, ulnar neuropathy, or similar neurological deficiencies
04

Study design

Phase
Not applicable
Primary purpose
Supportive care
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
21 participants (actual)

Study arms

  • Other
    Observation

    All participants will be monitored with EPAD system

    Device: EPAD monitoring system

Interventions

  • DeviceEPAD monitoring system

    EPAD system will be used as part of routine care

05

What researchers measure

Primary outcomes

  1. Somatosensory Evoked Potential Monitoring

    Recording of somatosensory evoked potential in patients undergoing genitourinary surgery

    Time frame: in the first 24 hours of postoperative period

06

Results

Posted Oct 30, 2019

Participant flow

Participant flow — Overall Study
MilestoneObservation
Started21
Completed0
Not completed21

Outcome measures

PrimarySomatosensory Evoked Potential Monitoring

Recording of somatosensory evoked potential in patients undergoing genitourinary surgery

Time frame:
in the first 24 hours of postoperative period

No measurements were reported for this outcome.

Adverse events

Collected over Adverse Events were collected over a 24 hour period.. Non-serious events are listed at a 0% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Observation0/21 (0%)0/21 (0%)0/21 (0%)

Baseline characteristics

Age, Continuous
Age, Continuous(years)Observation
Mean63 ± 11
Sex: Female, Male
Sex: Female, Male(Participants)Observation
Female7
Male14
Race (NIH/OMB)
Race (NIH/OMB)(Participants)Observation
American Indian or Alaska Native0
Asian0
Native Hawaiian or Other Pacific Islander0
Black or African American5
White16
More than one race0
Unknown or Not Reported0
Region of Enrollment
Region of Enrollment(participants)Observation
United States21
07

Study locations

1 site
  • Mayo Clinic Florida
    Jacksonville, Florida 32224, United States
08

References and documents

Study documents

  • Protocol and statistical analysis plan · May 4, 2017

Documents are hosted by the registry — open the source record to download them.

09

Registry details

Key details

Study ID
NCT03319407
Lead sponsor
Mayo Clinic
Responsible party
Robert McClain, MD (Principal Investigator, Mayo Clinic) — Principal investigator
First posted
Oct 24, 2017
Start date
Oct 5, 2017
Primary completion
Dec 30, 2018
Completion
Dec 30, 2018
Results posted
Oct 30, 2019
Last update
Apr 12, 2023

Study contacts

Robert McClain, MD
principal investigator · Mayo Clinic

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
Yes
View the source record on ClinicalTrials.gov ↗

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This study is terminated, as verified in Apr 2023. You cannot join it, but the record below documents what was studied.

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