CompletedNCT03295357EXTUB ECLSUpdated Sep 27, 2017

Extubation of Patients on ECLS is Associated With a Reduction in Complications Related to Mechanical Ventilation: Retrospective Single-centre Study

An observational study in Extra-Corporeal Life Support, sponsored by Centre Hospitalier Universitaire Dijon. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-09-27.

Sponsored by Centre Hospitalier Universitaire Dijon · Observational

Study type: Observational
Model: Other
Time perspective: Retrospective
Enrollment: 60
Ages: 18 Years and older
Sex: All

Study summary

There are no clear recommendations concerning the management of patients on ECLS (Extra-Corporeal Life Support). Many teams keep patients sedated until removal of the ECLS so as to avoid accidents, notably decannulation. Moreover, there are few publications on the subject, all the more so as the extubation of patients on ECLS (Extra-Corporeal Life Support) is a recent practice. Nonetheless, it is becoming more and more frequent in the cardiovascular ICU of Dijon University Hospital. We therefore wished to evaluate the benefits of this practice by comparing 2 populations: those with extubation while on ECLS (Extra-Corporeal Life Support) and those without.

Conditions studied

Extra-Corporeal Life Support

Who can participate

Ages eligible: 18 Years and older
Sexes eligible: All
Accepts healthy volunteers: No
Sampling method: Non-probability sample

Study population

Patients on ECLS

Inclusion criteria

Patients over 18 years who were placed on ECLS between 1/01/14 and 31/12/15

Exclusion criteria

Exclusion Criteria:

Patients under 18 years old
Patients on ECLS for a heart transplant
Patients who died within the first 48 hours following the initiation of ECLS

Study design

Observational model: Other
Time perspective: Retrospective
Enrollment: 60 participants (actual)
Patient registry: No

Groups and cohorts

Patients with extubation while on ECLS
Patients without extubation

What researchers measure

Primary outcomes

Incidence of VAP (ventilator-associated pneumonia) during hospitalisation in the ICU
Time frame: At baseline

Study locations

1 site

Chu Dijon Bourogne
Dijon, France

Registry details

Key details

Study ID: NCT03295357
Lead sponsor: Centre Hospitalier Universitaire Dijon
Responsible party: Sponsor
First posted: Sep 27, 2017
Start date: May 2016
Primary completion: Dec 2016
Completion: Dec 2016
Last update: Sep 27, 2017

Oversight

FDA-regulated drug: No
FDA-regulated device: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2017. You cannot join it, but the record below documents what was studied.

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Other studies from this sponsor

Centre Hospitalier Universitaire Dijon

Start the discussion