An interventional study of Combined rehabilitation and Linguistic rehabilitation in Aphasia, Acquired, sponsored by University Hospital, Toulouse. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2024-01-03.
Sponsored by University Hospital, Toulouse · Not applicable, Interventional, and Supportive care
Linguistic training is traditionally the gold standard for rehabilitation of aphasia after stroke and efficacy criteria count early stage, intensity as well as personalized treatment. To date, no clear evidence showed a specific effect of any therapy in the acute phase of aphasia after stroke. This study aims to compare the effect of a combined therapy (linguistic/communication) versus a linguistic therapy on communication performance in patients in the acute phase of aphasia after a first stroke.
Twenty to 25% of strokes cause aphasia. Speech and language therapy is the well-known standard treatment of aphasia after stroke although it is based on weak scientific evidence. To date, the efficacy criteria of aphasia rehabilitation are early stage, intensity as well as personalized treatment. Usually these patients receive in acute phase a linguistic training focused on the linguistic impairment. This approach is based on the cerebral plasticity postulate. However the superiority of this practice compared to other methods has never been shown. Moreover the benefit of the combination gathering linguistic treatment with communication treatment has to our knowledge never been studied.
In the present study investigators propose to compare the effect of a combined linguistic/communication rehabilitation versus a linguistic treatment. To do so, investigators will recruit patients with aphasia after a first stroke, in the acute phase. After a allocation to the " combined " and " linguistic " groups, all the patients will have a comprehensive language and neuropsychological assessment before and after 3 months of rehabilitation, and finally 6 months after the onset.
The "linguistic" group will have a rehabilitation only focused on linguistic processes whereas the "combined" group will have a linguistic training as well as communication training. The therapy will be personalized and the therapists will exclusively use standardized linguistic and/or communication toolboxes of rehabilitation containing dedicated activities.
Inclusion Criteria:
Exclusion Criteria:
Linguistic training as well as communication training.
Other: Combined rehabilitation
Rehabilitation only focused on linguistic processes.
Other: Linguistic rehabilitation
Linguistic training as well as communication training.
Rehabilitation only focused on linguistic processes.
Assessment of the communication performance.
Assessed by the Lillois communication test
Time frame: Month 3
Assessment of the communication performance.
Assessed by the Lillois communication test
Time frame: Month 6
Assessment of the linguistic performance.
Assessed by the "Score at understanding task".
Time frame: Month 3; Month 6
Assessment of the quality of life.
Assessed by the "Score at a specific quality of life scale ".
Time frame: Month 3; Month 6
This study is completed, as verified in Jan 2024. You cannot join it, but the record below documents what was studied.
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University Hospital, Toulouse