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CompletedNCT03283579Updated Jun 18, 2024

Fatty Acids and Attention Deficit and Hyperactivity Disorder Symptoms

An observational study in Child Behavior Problem, Attention Deficit Hyperactivity Disorder and Fatty Acid Deficiency, sponsored by Barcelona Institute for Global Health. Completed. Open to participants aged 4 Years to 8 Years. Per ClinicalTrials.gov, last updated 2024-06-18.

Sponsored by Barcelona Institute for Global Health · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
2,644
Ages
4 Years to 8 Years
Sex
All
01

Study summary

This study aimed to evaluate the longitudinal association between n-6:n-3 LCPUFAs ratio in cord blood and child ADHD symptoms at 4 and 7 years old. This study was based on the INMA project, a population-based birth cohort in Spain. Higher cord blood n-6:n-3 ratio was associated with higher subclinical ADHD symptoms during early and mid-childhood.

02

Conditions studied

  • Child Behavior Problem
  • Attention Deficit Hyperactivity Disorder
  • Fatty Acid Deficiency
03

Who can participate

Ages eligible
4 Years to 8 Years
Sexes eligible
All
Sampling method
Non-probability sample

Study population

This study was based on data from a population-based birth cohort, INMA (Infancia y Medio Ambiente [Environment and Childhood]) project, including four Spanish regions: Asturias (n=494) and Gipuzkoa (Basque Country) (n=638) on the Cantabrian coast, and Sabadell (Catalonia) (n=657) and Valencia (n=855) on the Mediterranean coast.

Eligibility criteria

Inclusion criteria:

  • Age 16 years or older
  • Singleton pregnancy
  • No use of assisted reproductive techniques
  • Intention to deliver at the reference hospital
  • Ability to speak and understand Spanish or a local language
04

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
2,644 participants (actual)
Patient registry
No

Groups and cohorts

  • Pregnant women
05

What researchers measure

Primary outcomes

  1. Fatty acid ratio in cord blood

    Time frame: 2004-2008

  2. ADHD 4 years old

    Time frame: 2008-2012

  3. ADHD 7 years old

    Time frame: 2012-2016

06

Study locations

No study locations are listed for this record.

07

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

08

Registry details

Key details

Study ID
NCT03283579
Lead sponsor
Barcelona Institute for Global Health
Responsible party
Sponsor
First posted
Sep 14, 2017
Start date
Nov 2003
Primary completion
Dec 2015
Completion
Dec 2015
Last update
Jun 18, 2024

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Sep 2017. You cannot join it, but the record below documents what was studied.

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