An interventional study of rTMS on ipsilesional M1 and tDCS on contralesional M1 in Stroke and Motor Disorder, sponsored by Samsung Medical Center. Completed. Open to participants aged 19 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-09-14.
Sponsored by Samsung Medical Center · Not applicable, Interventional, and Treatment
Among 46 studies in Stroke by Samsung Medical Center — 1 open to participants now, 2 under way, none of them phase 3. Stroke · Samsung Medical Center.
Among the 46 studies in Stroke by Samsung Medical Center, this one is the 24th largest by enrollment of the 31 interventional ones that give a count, is the only one that started in 2014, is one of 29 with no phase, and was the 16th registered.
8,255 studies on the registry are indexed under Stroke; 2,056 are open to participants now.
Browse Stroke studies →1 of the 46 studies in Stroke by Samsung Medical Center is open now, in 1 country. Recruiting first, the newest first:
Samsung Medical Center · Sites in Korea, Republic of
By country, each count listing its studies:
Of the 1,415 Stroke studies recruiting now, 697 (49%) set no upper age limit and 280 (20%) stop at 75 or younger; 77 take children under 18; 196 take healthy volunteers.
This study: 19 Years and older · all sexes · healthy volunteers too.
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46 studies; the count open now beside each. This study's row is marked.
First in 2009; this study’s year is marked. 1 started in 2014.
This study's enrollment of 24 is below the median of 49 across 6,024 interventional studies indexed under Stroke.
Median enrollment 32 across the 31 interventional studies, 110 across the 12 observational. Of the 34 that completed or were terminated, 0 (0%) have results posted.
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Samsung Medical Center is the lead sponsor of 1,011 studies on the registry; 152 are open to participants now.
Of its 7 completed or terminated interventional studies of FDA-regulated products, 1 (14%) have results posted.
None of the studies under way reaches primary completion within a year.
Among the 46 studies in Stroke by Samsung Medical Center, from their registry updates:
Nothing recorded among them since 2026-09-25.
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Repetitive transcranial magnetic stimulation (rTMS) or transcranial direct current stimulation (tDCS) has been used for the modulation of stroke patients' motor function by altering the cortical excitability. Recently, more challenging approaches, such as stimulation of two or more sites or use of dual modality have been studied in stroke patients. In this study, simultaneous stimulation using both rTMS and tDCS (dual-mode stimulation) over bilateral primary motor cortices (M1s) was investigated to compare its modulatory effects with single rTMS stimulation in subacute stroke patients.
Investigators assessed each patient's motor function using the Fugl-Meyer Assessment (FMA) score and acquired their resting-state fMRI (rs-fMRI) data at two times: prior to stimulation and 2 months after stimulation. Changes in rs-fMRI network measures were investigated between groups.
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Exclusion Criteria:
rTMS on ipsilesional M1 + tDCS on contralesional M1 10 Hz of rTMS was applied over the ipsilesional M1 for 20 minutes with simultaneous application of cathodal tDCS on the contralesional M1. Each participant's total FMA score is assessed and their resting-state fMRI data at two times: prior to stimulation (pre-stimulation) and 2 months after stimulation (post-stimulation) are acquired.
Device: rTMS on ipsilesional M1 · Device: tDCS on contralesional M1
rTMS on ipsilesional M1 10 Hz of rTMS over the ipsilesional M1 was applied for 20 minutes. Each participant's total FMA score is assessed and their resting-state fMRI data at two times: prior to stimulation (pre-stimulation) and 2 months after stimulation (post-stimulation) are acquired.
Device: rTMS on ipsilesional M1
Neuroimaging Assessment
Resting-state fMRI
Time frame: Change from baseline resting-state brain network at 8 weeks after intervention
No study locations are listed for this record.
PDFs hosted by the registry, ClinicalTrials.gov.
Plan to share: No
Ran from Mar 2014 to primary completion in Feb 2017, 35 months.
Of 3,108 non-industry interventional studies with no phase under Stroke, half reached primary completion within 23 months of starting (the median), counting those still running; a quarter within 10 and three quarters within 46. This study's 35 months is above that.
Counting every sponsor, half of 3,252 studies reached it within 23 months; a quarter within 10 and three quarters within 46.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.
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