An observational study in Prostate Cancer, sponsored by Mayo Clinic. Completed at 1 site in United States. Open to male participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2019-05-09.
Sponsored by Mayo Clinic · Observational
Biomarkers from circulating cell-free tumor DNA in peripheral blood will identify patients with metastatic prostate cancer diagnosed with C11 choline PET/CT who will benefit from metastasis-directed radiation, ablative therapies, and/or surgery. Tissue and blood will be collected before treatment. If patients receive androgen deprivation, then blood will be collected after neoadjuvant androgen deprivation but before radiation, ablative therapies, or surgery. Subsequent samples will be obtained at 3 months and 6 months following treatment, after which no further patient contact will occur.
6,370 studies on the registry are indexed under Prostatic Neoplasms; 1,400 are open to participants now.
This study's enrollment of 4 is below the median of 200 across 1,181 observational studies indexed under Prostatic Neoplasms.
Browse Prostatic Neoplasms studies →Mayo Clinic is the lead sponsor of 3,218 studies on the registry; 670 are open to participants now.
Of its 445 completed or terminated interventional studies of FDA-regulated products, 313 (70%) have results posted.
Counted across the registry records on this site, refreshed daily.
Men with metastatic prostate cancer
Exclusion Criteria:
Other: Blood draw · Procedure: Tissue biopsy
(2) 10 mL tubes will be collected
Tissue biopsy of metastatic tissue if undergoing clinical care-directed biopsy
Detect cell-free tumor DNA in patients with metastatic prostate cancer
tissue biopsy
Time frame: prior to treatment
Calculate cell-free tumor DNA in relation to metastasis-directed radiation and androgen deprivation therapy (ADT)
blood draw
Time frame: before and immediately after ADT and at 3 months and 6 months after radiation
Plan to share: No
This study is completed, as verified in May 2019. You cannot join it, but the record below documents what was studied.
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