An interventional study of selenium enriched parsnips and Conventional parsnips in Food Sensory Perception and Selenium Status, sponsored by Newcastle University. Status unknown at 1 site in United Kingdom. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-11-20.
Sponsored by Newcastle University · Not applicable, Interventional, and Basic science
Study aims to investigate 2 topics:
Flavour-Nutrient Learning (FNL) FNL proposes that personal food preferences may be influenced by unconscious mechanisms which operate to ensure the safeguarding of individual nutrient levels. The theory postulates that food preferences may change over time to address changing nutritional status (Yeomans, 2012).
This study aims to explore FNL in humans by investigating the preferences of participants with low and high blood-selenium levels in relation to selenium-enriched parsnips. Participants will be investigated in a two-week trial in which they will undertake two food sensory tests: one before, and one after, the two-week period where they will incorporate provided parsnips into their diet.
Some provided parsnips will contain higher levels of selenium than others, neither the participants nor the lead researcher will know which type of parsnip each participant receives.
It is hypothesised that the second food sensory test, performed after the intervention period, will show that participants of lower initial blood-selenium levels will demonstrate an increased liking for the selenium-enriched parsnips. This may demonstrate possible FNL in humans.
This will be assessed via blood tests before, during and after the trial in order to observe the blood-selenium levels of each participant.
It is hypothesised that the blood-selenium levels of participants of lower initial selenium readings will be the most improved upon consumption of selenium-enriched parsnips.
FNL Despite a wealth of animal studies (Amanoel et al, 2016; Bach et al, 2012), human FNL research is in relative infancy.
This study intends to investigate FNL in humans by exploring preferences of participants of different selenium-status regarding selenium-enriched parsnips, with non-enriched parsnips and other root vegetables to be used as comparators.
Participants will be assessed by means of food sensory tests and blood analysis before, during and after the trial period.
The trial aims to recruit 26 lower selenium-status participants of initial selenium-status approx. 70μg/L, and 26 higher selenium-status participants of initial selenium-status approx. 100μg/L (n=52). (Initial screening sample approx. n=120.) On initial screening, potential participants recording a selenium-status of under 28μg/L or over 400μg/L will be excluded (and their GP informed) for safety reasons.
Re parsnips:
Selenium-enriched parsnips: Se content approx. 0.30ppm. Placebo comparator: non-selenium-enriched parsnips: Se content approx. 0.06ppm. Treatment portion: 200g fresh weight per day for 14 days. Comparator vegetables: potato, celeriac, turnip.
This is deemed an important area for research as research suggests a trend towards selenium deficiency in the United Kingdom population (SACN, 2013). It is hoped the current study may inform the debate regarding the potential of improving United Kingdom's population selenium status via selenium-fortified foods.
Newcastle University is the lead sponsor of 60 studies on the registry; 15 are open to participants now.
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Exclusion Criteria:
Dietary Supplement: selenium enriched parsnips · Dietary Supplement: Conventional parsnips
Dietary Supplement: selenium enriched parsnips · Dietary Supplement: Conventional parsnips
Parsnips which have been grown in a selenium enriched environment
Parsnips which have been grown in a conventional environment
Food sensory perception
change from baseline sensory perception of food samples
Time frame: Baseline & post 14 weeks supplementation
Selenium status
Change from baseline selenium status
Time frame: Baseline, post 7 days supplementation ad post 14 days supplementation
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Nov 2017. You cannot join it, but the record below documents what was studied.
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Newcastle University