A Phase 2 interventional study of Ropivacaine and Saline in Total Knee Arthroplasty and Analgesia, sponsored by Asklepieion Voulas General Hospital. Completed. Per ClinicalTrials.gov, last updated 2017-07-02.
Sponsored by Asklepieion Voulas General Hospital · Phase 2, Interventional, and Treatment
40 patients ASA I-III, undergoing total knee arthroplasty were randomly assigned, into one of two groups, namely group LIA (n=20), where local infiltration analgesia would be administered intraoperatively; and group sham LIA (n=20), where sham injections of normal saline would be administered. All patients received a standardized multimodal approach, including pregabalin, adductor canal peripheral nervous blockade, spinal anaesthesia, paracetamol, and PCA with morphine. Morphine consumption during the first 24 hours postoperatively was measured and additionally the investigators recorded: Time of morphine first dose administration, NRS scores in static and dynamic conditions in 6 hours, 12 hours, 18 hours and 24 hours postoperatively, complications, patient satisfaction and duration of hospitalization.
1,190 studies on the registry are indexed under Agnosia; 508 are open to participants now.
This study's enrollment of 40 is below the median of 78 across 1,024 interventional studies indexed under Agnosia.
Browse Agnosia studies →Asklepieion Voulas General Hospital is the lead sponsor of 13 studies on the registry; 1 is open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Local infiltration analgesia
Drug: Ropivacaine
Saline injections
Other: Saline
Large volume local anaesthetic intraarticularly
sham injection
Morphine consumption
Time frame: 24 hours
NRS scores
Time frame: 24 hours
Complications
Time frame: 24 hours
Patient satisfaction
Patients asked whether they would choose the same anaesthetic management in a futue operaton: Yes / No
Time frame: 24 hours
Duration of hospitalization
Number of days patients remain in the hospital postoperatively
Time frame: 1 month
No study locations are listed for this record.
Plan to share: No
This study is completed, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.
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Asklepieion Voulas General Hospital