An observational study in Sjogren's Syndrome and Vitamin D Deficiency, sponsored by University of Pennsylvania. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2021-08-04.
Sponsored by University of Pennsylvania · Observational
Patients who are suspected of or diagnosed with Sjogren's disease will be evaluated for ocular symptoms and corneal nerve morphology. We are specifically interested in the relationship between Vitamin D level and aberrations in the morphology of the corneal nerves.
Patients with either suspected or confirmed diagnosis of Sjogren's disease will be recruited to participate. Participation will involve the completion of a brief survey (the OSDI), corneal evaluation with an aesthesiometer, corneal staining with fluorescein and lissamine green, and finally measurement of tear-film breakup time. In addition, participants will have their corneal nerve morphology evaluated with the Heidelberg confocal microscope and finally they will have a blood draw performed to assess vitamin D level.
371 studies on the registry are indexed under Sjogren's Syndrome; 104 are open to participants now.
This study's enrollment of 100 is below the median of 114 across 113 observational studies indexed under Sjogren's Syndrome.
Browse Sjogren's Syndrome studies →University of Pennsylvania is the lead sponsor of 1,635 studies on the registry; 239 are open to participants now.
Of its 154 completed or terminated interventional studies of FDA-regulated products, 104 (68%) have results posted.
Counted across the registry records on this site, refreshed daily.
Suspected or confirmed Sjogren's patients
Exclusion Criteria:
Corneal Nerve Morphology
Heidelberg Retina Tomograph with the Rostock Cornea Module
Time frame: one time exam
Vitamin D Level
serum
Time frame: one time exam at baseline, day 1
vital dye staining
corneal staining
Time frame: one time exam at baseline, day 1
This study is completed, as verified in Aug 2021. You cannot join it, but the record below documents what was studied.
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University of Pennsylvania