An interventional study of Positive pressure extubation and Traditional during extubation in Complication, sponsored by Hospital Donación Francisco Santojanni. Status unknown at 1 site in Argentina. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-06-05.
Sponsored by Hospital Donación Francisco Santojanni · Not applicable, Interventional, and Treatment
Laboratory studies suggest extubation with positive pressure because it reduces the volume of secretions filtered into the distal airway. The aim of this non inferiority study is to evaluate the safety of the extubation technique under positive pressure with respect to the traditional technique (with suction and without positive pressure in the airways).
The extubation procedure consists of the removal of the endotracheal tube when it is no longer required. The literature reports two methods of extubation: the named traditional method (with suction and without positive pressure in the airways) and the positive pressure method. Laboratory studies suggest extubation at positive pressure because it reduces the volume of secretions filtered into the distal airway. Prior to apply it into clinical practice the investigators of this study consider is a priority to guarantee the safety of the positive pressure extubation method in terms of presence of complications.
The aim of this non-inferiority study is to compare the incidence of complications between both extubation techniques in adult patients with invasive mechanical ventilation.
The hypothesis of this study is that applying positive pressure during cuff deflation and extubation is not inferior to the traditional method in the incidence of complications.
Hospital Donación Francisco Santojanni is the lead sponsor of 6 studies on the registry; none are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Positive pressure extubation is used for patients in this group.
Procedure: Positive pressure extubation
Traditional extubation is used for patients in this group.
Procedure: Traditional during extubation
Positive pressure ventilation without endotracheal aspiration/suction during extubation procedure.
Spontaneous ventilation with endotracheal aspiration/suction during extubation procedure.
Presence/A presence/absence of complications after extubation
Clinical Evidence of at least one of the next complications: persistent cough, airway obstruction, post-obstructive pulmonary edema, bronchospasm, desaturation, vomiting, tachycardia, arterial hypertension.
Time frame: 60 minutes
Pneumonia
Presence of fever, leukocytosis, purulent secretions and a new pulmonary infiltrate on chest radiography
Time frame: 72 hours
Reintubation
Intubation requirement after extubation
Time frame: 72 hours
Plan to share: Undecided
This study is status unknown, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.
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Hospital Donación Francisco Santojanni