An interventional study of low molecular weight heparin in Liver Cirrhosis and Portal Hypertension, sponsored by West China Hospital. Status unknown at 1 site in China. Open to participants aged 18 Years to 75 Years. Per ClinicalTrials.gov, last updated 2019-01-08.
Sponsored by West China Hospital · Not applicable, Interventional, and Treatment
Transjugular intrahepatic portosystemic shunt (TIPS) dysfunction is defined as a loss of decompression of the portal venous system due to occlusion or stenosis of the TIPS. Occlusion of the TIPS can either be due to thrombosis or hyperplasia of the intima. Thrombosis of the TIPS usually occurs early and can happen within 24 hours of TIPS creation. The frequency of this complication is on the order of 10%-15% when bare stents are used. Post-TIPS short-term low molecular weight heparin (LMWH) was used to prevent the early thrombosis formation. Weather post-TIPS LMWH was necessary when polytetrafluoroethylene-covered stent was used during TIPS creation was not answered. The present study was designed to evaluate the effect of short-term use of LMWH on early TIPS dysfunction.
1,642 studies on the registry are indexed under Liver Cirrhosis; 358 are open to participants now.
This study's planned enrollment of 117 is above the median of 72 across 995 interventional studies indexed under Liver Cirrhosis.
Browse Liver Cirrhosis studies →West China Hospital is the lead sponsor of 483 studies on the registry; 240 are open to participants now.
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Exclusion Criteria:
After TIPS procedure was performed, low molecular weight heparin was given for three days.
Drug: low molecular weight heparin
After TIPS procedure was performed, no low molecular weight heparin was given.
After TIPS procedure was performed, low molecular weight heparin was given for three days.
TIPS patency rate
Analysis
Time frame: one year
LMWH-related complication
Analysis
Time frame: one month
Mortality rate
Analysis
Time frame: one year
Plan to share: Undecided
No publications or documents are linked to this record.
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West China Hospital