An interventional study of Laparoscopic Assisted Transanal Total Mesorectal Excision in Rectal Cancer, sponsored by Assiut University. Status unknown at 1 site in Egypt. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2017-05-31.
Sponsored by Assiut University · Not applicable, Interventional, and Treatment
Rectal cancer is one of the frequent malignant neoplasms ,Total mesorectal excision (TME) has become the gold standard treatment for middle and lower rectal cancers. Laparoscopic TME still be difficult in patients with low rectal tumors, narrow pelvic anatomy, male sex or high body mass index . Difficult visualization of the pelvic anatomy along with the limitation of rigid laparoscopic instruments may affect the quality of oncological outcomes and increase the risks of injuries during surgery. A down to up approach via transanal total mesorectal excision (TaTME) technique may overcome these problems
This clinical trial will be conducted at general surgery department of Assiut University Hospital .
.
1,762 studies on the registry are indexed under Rectal Neoplasms; 518 are open to participants now.
This study's planned enrollment of 100 is above the median of 65 across 1,298 interventional studies indexed under Rectal Neoplasms.
Browse Rectal Neoplasms studies →Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.
Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.
Counted across the registry records on this site, refreshed daily.
rectal cancer histologically proven through biopsy
Exclusion Criteria:
T4 tumours not responding to neoadjuvant chemo- radiotherapy
Laparoscopic Assisted Transanal Total Mesorectal Excision
Procedure: Laparoscopic Assisted Transanal Total Mesorectal Excision
* Abdominal approach with laparoscopic mobilization of the left colon * Laparoscopic isolation and transection of inferior mesenteric vessels . * Transabdominal dissection of the upper rectum and mesorectam. * Insertion of transanal platform and the creation of pneumorectum. * Occlusion of rectum 2 cm distal to the rectal lesion via purse string. * Transanal dissection of lower and mid mesorectam * The specimen will be extracted transanally
intraoperative complication
complication occured intraoperatively or on the first day of surgery
Time frame: 1 day
resection margin
circumferential resection margin microscopic examination
Time frame: 1 years
Mortality rate
rate of death
Time frame: 1 years
morbidity rate
rate of postoperative morbidity
Time frame: 1 year
recurrance rate
rate of local recurance( by CT scan )
Time frame: 2 years
Anorectal function outcomes
manometric assessment of anorectal function
Time frame: 2 years
Sexual functional outcomes
sexual function with IIEF(International Index of Erectile Function) questionnaire
Time frame: 2 years
Mesorectal completeness
The quality of the mesorectum or TME specimen(pathological examination)
Time frame: 1 year
Plan to share: No
This study is status unknown, as verified in May 2017. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Assiut University