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Status unknownNCT03165266Updated May 24, 2017

Right Ventricular Involvement in Inferior Myocardial Infarction Patients Using 2 Dimensional Speckle Tracking Echocardiography

An observational study in Acute Myocardial Infarction of Inferior Wall Involving Right Ventricle (Disorder), sponsored by Assiut University. Status unknown. Open to participants aged 18 Years to 100 Years. Per ClinicalTrials.gov, last updated 2017-05-24.

Sponsored by Assiut University · Observational

The sponsor has not verified this record recently (last verified May 2017), so the status shown — last known as Not yet recruiting — may be out of date.
Study type
Observational
Model
Case-only
Time perspective
Prospective
Enrollment
100
Ages
18 Years to 100 Years
Sex
All
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Study summary

Right ventricular infarction usually occurs in association with inferior myocardial infarction in about 10-50% of the cases. Currently the presence of elevation in right pericordial leads is the most powerful indicator of right ventricular infarction.

The incidence of right ventricular infarction is more in postmortem studies,meaning that Right ventricular infarction is underestimated, possible explanation for this difference could be explained that electrocardiographic sign of Right ventricular infarction disappear early or patients presented late.

Read the detailed description

The incidence of right ventricular infarction is more in postmortem studies,meaning that Right ventricular infarction is underestimated, possible explanation for this difference could be explained that electrocardiographic sign of Right ventricular infarction disappear early or patients presented late

The role of Right ventricular systolic function in inferior myocardial infarction patients with or without Right ventricular infarction Had been studied. In our study we will Assess Right Ventricular infarction in patients of acute inferior myocardial infarction undergoing primary percutaneous coronary intervention by correlating electrocardiogram, Right ventricular systolic function by echocardiography with the angiographic finding.

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Conditions studied

  • Acute Myocardial Infarction of Inferior Wall Involving Right Ventricle (Disorder)
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In context

Myocardial Infarction

2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.

This study's planned enrollment of 100 is below the median of 500 across 983 observational studies indexed under Myocardial Infarction.

Browse Myocardial Infarction studies →

Lead sponsor

Assiut University is the lead sponsor of 4,901 studies on the registry; 2,098 are open to participants now.

Of its 13 completed or terminated interventional studies of FDA-regulated products, 0 (0%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 100 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

the study include patients with Acute inferior Myocardial in Assuit University Hospital in the duration beginning from June 2017 .

Inclusion criteria

  1. Patients of recent acute inferior myocardial infarction.
  2. Patients managed by Primary percutaneous coronary intervention.

Exclusion criteria

Exclusion Criteria:

  1. Pervious inferior Myocardial Infarction.
  2. Inferior Myocardial Infarction treated by thrombolytic therapy.
  3. Chronic pulmonary disease.
  4. estimatedPulmonary Artery Systolic Pressure ≥35 mmHg by Echocardiography.
  5. Valvular heart disease. 6- Dilated cardio-myopathy patients.
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Study design

Observational model
Case-only
Time perspective
Prospective
Enrollment
100 participants (estimated)
Patient registry
No

Interventions

  • Diagnostic testTwo dimensional Echocardiography

    I- Routine transthoracic assessment for Left Atrium and Left Ventricle dimensions : II- transthoracic assessment of the Right ventricular systolic function by: 1. . Right Ventricle fractional area change. 2. . Tricuspid annular plane systolic excursion . 3. . Tissue Doppler derived tricuspid annular systolic velocity. 4. . Right ventricle myocardial performance index . III- Assessment of Right ventricular diastolic function: is carried out by pulsed Doppler of the tricuspid inflow, or tissue Doppler of the lateral tricuspid annulus. IV Assessment of Right Ventricle chamber quantification: * Right ventricular basal, mid ,and longitudinal dimensions. * Right ventricular Outflow Tract, and wall thickness V- Assessment of right atrial major ,and minor dimensions ,and right atrial End- systolic area IV- Assessment of longitudinal Right ventricular strain and strain rate by speckle tracking

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What researchers measure

Primary outcomes

  1. Right ventricular dysfunction

    right ventricular dysfunction by Echocardiography as indicator of right ventricular infarction in inferior wll myocardial patients

    Time frame: 3days

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Study locations

No study locations are listed for this record.

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References and documents

Publications

  • Andersen HR, Nielsen D, Falk E. Right ventricular infarction: larger enzyme release with posterior than with anterior involvement. Int J Cardiol. 1989 Mar;22(3):347-55. doi: 10.1016/0167-5273(89)90276-3. PubMed 2707915 ↗
  • Andersen HR, Falk E, Nielsen D. Right ventricular infarction: frequency, size and topography in coronary heart disease: a prospective study comprising 107 consecutive autopsies from a coronary care unit. J Am Coll Cardiol. 1987 Dec;10(6):1223-32. doi: 10.1016/s0735-1097(87)80122-5. PubMed 3680789 ↗
  • Wagner GS, Macfarlane P, Wellens H, Josephson M, Gorgels A, Mirvis DM, Pahlm O, Surawicz B, Kligfield P, Childers R, Gettes LS, Bailey JJ, Deal BJ, Gorgels A, Hancock EW, Kors JA, Mason JW, Okin P, Rautaharju PM, van Herpen G; American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; American College of Cardiology Foundation; Heart Rhythm Society. AHA/ACCF/HRS recommendations for the standardization and interpretation of the electrocardiogram: part VI: acute ischemia/infarction: a scientific statement from the American Heart Association Electrocardiography and Arrhythmias Committee, Council on Clinical Cardiology; the American College of Cardiology Foundation; and the Heart Rhythm Society. Endorsed by the International Society for Computerized Electrocardiology. J Am Coll Cardiol. 2009 Mar 17;53(11):1003-11. doi: 10.1016/j.jacc.2008.12.016. No abstract available. PubMed 19281933 ↗
  • Javed S, Rajani AR, Govindaswamy P, Radaideh GA, Abubaraka HA, Qureshi TI, Arshad HB. Right ventricular involvement in patients with inferior myocardial infarction, correlation of electrocardiographic findings with echocardiography data. J Pak Med Assoc. 2017 Mar;67(3):442-445. PubMed 28303997 ↗
  • Zornoff LA, Skali H, Pfeffer MA, St John Sutton M, Rouleau JL, Lamas GA, Plappert T, Rouleau JR, Moye LA, Lewis SJ, Braunwald E, Solomon SD; SAVE Investigators. Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction. J Am Coll Cardiol. 2002 May 1;39(9):1450-5. doi: 10.1016/s0735-1097(02)01804-1. PubMed 11985906 ↗
  • O'Rourke RA, Dell'Italia LJ. Diagnosis and management of right ventricular myocardial infarction. Curr Probl Cardiol. 2004 Jan;29(1):6-47. doi: 10.1016/j.cpcardiol.2003.08.003. No abstract available. PubMed 14872197 ↗
  • Bayata S, Avci E, Yesil M, Arikan E, Postaci N, Tuluce SY. Tricuspid annular motion in right coronary artery-related acute inferior myocardial infarction with or without right ventricular involvement. Anadolu Kardiyol Derg. 2011 Sep;11(6):504-8. doi: 10.5152/akd.2011.134. Epub 2011 Jul 25. PubMed 21788200 ↗
  • Rudski LG, Lai WW, Afilalo J, Hua L, Handschumacher MD, Chandrasekaran K, Solomon SD, Louie EK, Schiller NB. Guidelines for the echocardiographic assessment of the right heart in adults: a report from the American Society of Echocardiography endorsed by the European Association of Echocardiography, a registered branch of the European Society of Cardiology, and the Canadian Society of Echocardiography. J Am Soc Echocardiogr. 2010 Jul;23(7):685-713; quiz 786-8. doi: 10.1016/j.echo.2010.05.010. No abstract available. PubMed 20620859 ↗
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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 24, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03165266
Lead sponsor
Assiut University
Responsible party
EGAbdelrhman (principal investgator, Assiut University) — Principal investigator
First posted
May 24, 2017
Start date
Jun 1, 2017 (estimated)
Primary completion
Jan 1, 2018 (estimated)
Completion
Feb 28, 2018 (estimated)
Last update
May 24, 2017

Study contacts

Hossam H El-Araby, Prof
Contact
hosam_hasan@hotmail.com.com
00201223971327
Hatem A Helmy, Ass.Prof
Contact
hatem19652007@yahoo.com
00201005212162
Marwa M Abdelmohsen, Lecturer
study chair · Assiut University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2017. You cannot join it, but the record below documents what was studied.

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