An observational study in Osteoarthritis, sponsored by The Republican Research and Practical Center for Epidemiology and Microbiology. Completed at 1 site in Belarus. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2019-01-09.
Sponsored by The Republican Research and Practical Center for Epidemiology and Microbiology · Observational
This study evaluates laboratory-based method to estimate the degrees of activity of medium and large joint osteoarthritis.
Osteoarthritis (OA) is a chronic progressive disease, characterized by degradation of joint cartilage, synovial inflammation and joint dysfunction. This study evaluates laboratory-based method to estimate the degrees of activity of medium and large joint OA. Samples of synovial fluid (SF) from the patients with the OA (ICD-10 codes: M15, M16 and M17) will be assessed for T-cell subsets, msast cells, fibroblast-like synoviocytes (FLS) and macrophage-like synoviocytes (MLS) by flow cytometry. Subpopulations of blood T-cells involved in the inflammation will also be assayed. Standard clinical investigation will be performed and the results will be used to estimate the laboratory criteria or degrees of activity of medium and large joint OA.
Patients with medium and large joint osteoarthritis
Exclusion Criteria:
Patients with medium and large joint osteoarthritis
Control group of healthy persons
The sensitivity of the proposed laboratory-based method in the diagnostics of the activity of osteoarthritis
The sensitivity of the proposed laboratory-based method in the diagnostics of the activity of medium and large joint osteoarthritis
Time frame: 2 month
Plan to share: No
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This study is completed, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
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The Republican Research and Practical Center for Epidemiology and Microbiology