An observational study in Ulcerative Colitis, sponsored by Xiuli Zuo. Status unknown at 1 site in China. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-05-12.
Sponsored by Xiuli Zuo · Observational
We analyzed the diversity of the fungal and bacterial within colon mucosa between patients with different degree of inflammation of Ulcerative Colitis.
In recent years, the relationship of intestinal fungus with inflammatory bowel disease was gradually revealed. We divided the patients with ulcerative colitis into three groups on the basis of World Gastroenterology Organisation (WGO) classification about inflammation degree and progress classification and established the healthy control group. Analyzing the diversity of the fungal and bacterial within colon mucosa between patients with different clinical classification, for example, the proportion of bacteria and fungi, the proportion of candida albicans, the proportion of yeasts, and so on.
1,073 studies on the registry are indexed under Colitis; 131 are open to participants now.
This study's planned enrollment of 50 is below the median of 105 across 247 observational studies indexed under Colitis.
Browse Colitis studies →Xiuli Zuo is the lead sponsor of 10 studies on the registry; 5 are open to participants now.
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Consecutive patients under endoscopic surveillance or examination at Qilu Hospital were considered for inclusion.
Exclusion Criteria:
We analysed the diversity of the fungal and bacterial in patients with Ulcerative Colitis (UC). We take 2 pieces of biopsies in the sigmoid colon mucosa inflammation area during the colonoscopy and then perform gene sequencing.
Other: ulcerative colitis
Analysing the diversity of the fungal and bacterial in patients without ulcerative colitis. We take 2 pieces of biopsies in the sigmoid colon mucosa during the colonoscopy and then perform gene sequencing.
Other: Control
We take 2 pieces of biopsies in the sigmoid colon mucosa inflammation area during the colonoscopy and then perform gene sequencing.
Also known as: Patients With ulcerative colitis
We take 2 pieces of biopsies in the sigmoid colon mucosa during the colonoscopy and then perform gene sequencing.
Also known as: Patients Without ulcerative colitis
fungus detection rate
Fungi detection rate was defined as the percentage of patients in whose colonic mucosa at least one kind of fungus were identified.
Time frame: 6 months
yeasts detection rate
Yeasts detection rate was defined as the percentage of patients in whose colonic mucosa yeasts were identified.
Time frame: 6 months
candida albicans detection rate
Candida albicans detection rate was defined as the percentage of patients in whose colonic mucosa candida albicans were identified.
Time frame: 6 months
Plan to share: No
This study is status unknown, as verified in May 2017. You cannot join it, but the record below documents what was studied.
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Xiuli Zuo