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CompletedNCT03136939Updated Jul 2, 2017

Study of IGRP-specific T Cell in Peripheral Blood of Type 1 Diabetes Mellitus

An observational study in Diabetes Mellitus, sponsored by First Affiliated Hospital of Zhejiang University. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2017-07-02.

Sponsored by First Affiliated Hospital of Zhejiang University · Observational

Study type
Observational
Model
Case-control
Time perspective
Prospective
Enrollment
30
Sex
All
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Study summary

10 type 1 diabetes, 10 type 2 diabetes and 10 healthy controls matched with age and sex were enrolled in our study and their periphera blood mononuclear cells (PBMC) were isolated. We implemented ELISPOT(Enzyme-linked Immunospot Assay) to detect the interferon-γ (IFN-γ)which secreted by IGRP-specific T cell. Results were compared between these groups.

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Conditions studied

03

In context

Diabetes Mellitus

10,923 studies on the registry are indexed under Diabetes Mellitus; 1,318 are open to participants now.

This study's enrollment of 30 is below the median of 233 across 2,218 observational studies indexed under Diabetes Mellitus.

Browse Diabetes Mellitus studies →

Lead sponsor

First Affiliated Hospital of Zhejiang University is the lead sponsor of 255 studies on the registry; 139 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
Yes
Sampling method
Non-probability sample

Study population

patients of diabetes and healthy controls

Inclusion criteria

  • the criteria of type 1 and type 2 diabetes

Exclusion criteria

Exclusion Criteria:

  • no diabetes
05

Study design

Observational model
Case-control
Time perspective
Prospective
Enrollment
30 participants (actual)
Patient registry
No

Groups and cohorts

  • type 1 diabetes

    Other: No intervention

  • type 2 diabetes

    Other: No intervention

  • healthy people

    Other: No intervention

Interventions

  • OtherNo intervention

    No intervention

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What researchers measure

Primary outcomes

  1. the rate of positive reactivation against the IGRP epitopes

    Time frame: 5 months

07

Study locations

1 site
  • Department of Endocrinology, the First Affiliated Hospital to Zhejiang University School of Medicine
    Hangzhou, Zhejiang 310003, China
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References and documents

Individual participant data

Plan to share: No — IPD be shared while request by email

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jul 2, 2017, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT03136939
Lead sponsor
First Affiliated Hospital of Zhejiang University
Responsible party
Sponsor
First posted
May 2, 2017
Start date
Jan 1, 2017
Primary completion
May 30, 2017
Completion
May 31, 2017
Last update
Jul 2, 2017

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Apr 2017. You cannot join it, but the record below documents what was studied.

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