An observational study in Lymphoma and Cancer, sponsored by Centre Hospitalier Universitaire, Amiens. Withdrawn. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-01-16.
Sponsored by Centre Hospitalier Universitaire, Amiens · Observational
Cancer is the leading cause of death in man and the second leading cause in women with 85,000 and 63,000 deaths, respectively, in 2012. A working group led by Holly L. Howe, PhD, in 2002 defined primary neoplasia Such as the occurrence and diagnosis of two or more independent neoplasms of different histology in the same patient. The occurrence of a new cancer has become more frequent in recent years: the prevalence of multiple primary neoplasia (NPM) is estimated between 0.73% and 11.7%. According to the French data, the risk of second cancer in people who have already had a first cancer is increased by 36% compared to the general population. Several studies have reported an increase in the risk of cancer after treatment of lymphoma but there are currently no studies on the occurrence of lymphoma and cancer of synchronous occurrence.
In our department, 19 patients presented cancer and lymphoma synchronously, that is to say 6 months between 2007 and 2012.
The main objective is to show that there is an increase in the incidence of cancers in patients diagnosed for lymphoma synchronously. Secondary objectives are to describe the clinical and biological characteristics of the patients concerned and to formulate hypotheses on the physiopathological mechanisms involved: peri-tumoral B-cell lymphoproliferation, alteration of the immune system or rearrangement of the BCR.
In a second step, the investigator could propose a multicenter epidemiological study using data from the different Cancer Registries. If results are confirmed in a larger cohort, recommendations could be made.
5,578 studies on the registry are indexed under Lymphoma; 825 are open to participants now.
Browse Lymphoma studies →Centre Hospitalier Universitaire, Amiens is the lead sponsor of 576 studies on the registry; 178 are open to participants now.
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Retrospective study on data and elements of the human body (anatomo-pathological blade) over a period of 6 years in patients with synchronous lymphoma
Exclusion Criteria:
Show an increase in incidence of cancers in patients with synchronous lymphoma
Analysis of the occurrence of cancer and lymphoma within 6 months between 2007 and 2012
Time frame: 5 years
No study locations are listed for this record.
This study is withdrawn, as verified in Jan 2026. You cannot join it, but the record below documents what was studied.
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Centre Hospitalier Universitaire, Amiens