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CompletedNCT03059680Updated Feb 20, 2020

Effects of Implementing a High Potassium Diet in Heart Failure Patients

An interventional study of High potassium diet in Heart Failure, sponsored by Samuel Lunenfeld Research Institute, Mount Sinai Hospital. Completed. Open to participants aged 18 Years to 80 Years. Per ClinicalTrials.gov, last updated 2020-02-20.

Sponsored by Samuel Lunenfeld Research Institute, Mount Sinai Hospital · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
18 Years to 80 Years
Sex
All
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Study summary

This study evaluates the safety and physiologic effects of increasing dietary potassium intake in individuals with heart failure.

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Conditions studied

  • Heart Failure

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Keywords

  • Potassium
  • Nutrition
03

In context

Heart Failure

5,697 studies on the registry are indexed under Heart Failure; 1,219 are open to participants now.

This study's enrollment of 30 is below the median of 72 across 3,733 interventional studies indexed under Heart Failure.

Browse Heart Failure studies →

Lead sponsor

Samuel Lunenfeld Research Institute, Mount Sinai Hospital is the lead sponsor of 135 studies on the registry; 17 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • All patients classified as having HF, both systolic and diastolic.
  • New York Heart Association class II-III symptoms.
  • Treatment with an beta blocker, ACE inhibitor, or angiotensin receptor blocker without any adjustment over the previous month
  • Intake at baseline of ≤ 3 servings of fruits and vegetables per day. Servings defined by Health Canada's food guide.

Exclusion criteria

Exclusion Criteria:

  • Patients with an episode of decompensated heart failure, acute coronary syndrome, or revascularization within the previous 3 months of study inclusion.
  • Patients receiving insulin therapy
  • Glomerular filtration rate \< 40mL/min/1.73 m2
  • Pregnancy and lactation (women of childbearing potential will be included but will have to have a negative pregnancy test prior to inclusion).
  • Inability to provide informed consent.
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Experimental
    High potassium diet group

    Individuals in this arm were asked to increase dietary potassium intake over a 4 week period. This was achieved through an increase in consumption of fruits and vegetables.

    Other: High potassium diet

  • No intervention
    Usual diet group

    Individuals in this group were asked to continue habitual dietary intake

Interventions

  • OtherHigh potassium diet

    An increase in consumption of high potassium fruits and vegetables

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What researchers measure

Primary outcomes

  1. Serum potassium concentration

    Time frame: 10 days and 3 weeks

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 20, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT03059680
Lead sponsor
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Responsible party
Sponsor
First posted
Feb 23, 2017
Start date
Jan 2012
Primary completion
Dec 2016
Completion
Jan 2017
Last update
Feb 20, 2020

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2020. You cannot join it, but the record below documents what was studied.

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