An interventional study of MBT-CD in Conduct Disorder, sponsored by Heidelberg University. Completed at 1 site in Germany. Open to participants aged 11 Years to 18 Years. Per ClinicalTrials.gov, last updated 2022-05-18.
Sponsored by Heidelberg University · Not applicable, Interventional, and Treatment
A feasibility and pilot trial to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)"
Background: Conduct Disorder is a severe and complex mental disorder with the highest incidence in adolescence. Previous studies have shown that family-oriented interventions are effective in the treatment of Conduct Disorder. However, most therapies focus rather on symptom management and less on etiological causes without inclusion of the family in the therapeutic process. Previous research has linked specific symptoms of Conduct Disorder with deficits in mentalization ability. Mentalization is the ability to perceive one's own and other's behavior as the product of affective and cognitive mental states. Low or missing mentalization abilities are regarded as a risk factor for the development and chronification of Conduct Disorder.
Aims: The study aims to investigate the feasibility of a newly manualized psychotherapy "Mentalization-Based Training for Adolescents with Conduct Disorder (MBT-CD)" that strives to decrease symptoms associated with Conduct Disorder by increasing mentalization in adolescents and their families.
Methods: The study is feasibility and piolot trial, carried out in Heidelberg (Germany), and Mainz (Germany). Adolescents aged between 11-18, who meet the DSM-5 criteria for Conduct Disorder will receive MBT-CD. Times of measurement: t0 (Screening), T1 (Baseline, at the beginning of therapy), T2 (3 months after the beginning of therapy), T3 (at the end of therapy, after 6 months), T4 (follow-up, after 9 months).
101 studies on the registry are indexed under Conduct Disorder; 15 are open to participants now.
This study's enrollment of 45 is below the median of 124 across 80 interventional studies indexed under Conduct Disorder.
Browse Conduct Disorder studies →Heidelberg University is the lead sponsor of 287 studies on the registry; 19 are open to participants now.
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Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
DSM diagnostic criteria
The American Psychiatric Association’s manual of mental health diagnoses. DSM-5 (2013, revised as DSM-5-TR in 2022) replaced DSM-IV, and some studies still name the older edition. “Meets DSM criteria for …” means diagnosed by that edition’s diagnostic criteria, usually by a clinician in an interview.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Informed consent
Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.
You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.
Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.
Mentalization-based treatment program
Other: MBT-CD
MBT-CD is a disorder-specific modification of MBT, initially developed for patients with Borderline Personality Disorder. It is a manualized and psychodynamically oriented psychotherapy with the aim to increase the mentalization capacity of adolescents in close relationships. The therapy consists of 2 psychoeducational group sessions, 30 individual therapy sessions and 10 family sessions. The average duration of therapy is 6 months.
Structured Clinical Interview for DSM-IV Axis II Disorders (SCID-II)
Time frame: Change from baseline in SCID-II at 12 months (at the end of therapy)
Subtypes of Antisocial Behaviour Questionnaire (STAB)
Time frame: Change from baseline in STAB at 6 months
Subtypes of Antisocial Behaviour Questionnaire (STAB)
Time frame: Change from baseline in STAB at 12 months (at the end of therapy)
Subtypes of Antisocial Behaviour Questionnaire (STAB)
Time frame: Change from baseline in STAB at 18 months (follow-up)
Reactive-Proactive-Aggression Questionnaire (RPQ)
Time frame: Change from baseline in RPQ at 6 months
Reactive-Proactive-Aggression Questionnaire (RPQ)
Time frame: Change from baseline in RPQ at 12 months (at the end of therapy)
Reactive-Proactive-Aggression Questionnaire (RPQ)
Time frame: Change from baseline in RPQ at 18 months (follow-up)
Global Assessment of Functioning (GAF)
Time frame: Change from baseline in GAF at 12 months (at the end of therapy)
Clinical Global Impression (CGI-SI)
Time frame: Change from baseline in CGI-SI at 12 months (at the end of therapy)
Levels of Personality Functioning - Questionnaire Adolescence (LoPF-QA)
Time frame: Change from baseline in LoPF-QA at 12 months (at the end of therapy)
Levels of Personality Functioning - Questionnaire Adolescence (LoPF-QA)
Time frame: Change from baseline in LoPF-QA at 18 months (follow-up)
Reflective Functioning Questionnaire (RFQ)
Time frame: Change from baseline in RFQ at 12 months (at the end of therapy)
Reflective Functioning Questionnaire (RFQ)
Time frame: Change from baseline in RFQ at 18 months (follow-up)
Movie for the Assessment of Social Cognition (MASC)
Time frame: Change from baseline in MASC at 12 months (at the end of therapy)
10 round Trust Game Task (TGT)
Time frame: Change from baseline in TGT at 12 months (at the end of therapy)
Social Hierarchy Task (SHT)
Time frame: Change from baseline in SHT at 12 months (at the end of therapy)
Approach-Avoidance Task (AAT)
Time frame: Change from baseline in AAT at 12 months (at the end of therapy)
Symptom Checklist-90-Revised (SCL-90R)
Time frame: Change from baseline in SCL-90R at 12 months (at the end of therapy)
Stress Index for Parents of Adolescents (SIPA)
Time frame: Change from baseline in SIPA at 12 months (at the end of therapy)
Stress Index for Parents of Adolescents (SIPA)
Time frame: Change from baseline in SIPA at 18 months (follow-up)
drop-out rates
Time frame: after 12 months (at the end of therapy)
cost-effectiveness
Cost-effectiveness will be measured by participation in training/school, rehospitalization, internment
Time frame: after 12 months (at the end of therapy)
Working Alliance Inventory (WAI)
Treatment related variable (moderator)
Time frame: Change from baseline in WAI at 6 months
Working Alliance Inventory (WAI)
Treatment related variable (moderator)
Time frame: Change from baseline in WAI at 12 months (at the end of therapy)
Experiences in Close Relationships - Revised (ECR-R)
Treatment related variable (moderator)
Time frame: Change from baseline in ECR-R at 12 months (at the end of therapy)
Emotion Regulation Questionnaire (ERQ)
Treatment related variable (moderator)
Time frame: Change from baseline in ERQ at 12 months (at the end of therapy)
Emotion Regulation Questionnaire (ERQ)
Treatment related variable (moderator)
Time frame: Change from baseline in ERQ at 18 months (follow-up)
Zurich Brief Questionnaire for the Assessment of Parental Behaviors (ZKE)
Treatment related variable (moderator)
Time frame: Change from baseline in ZKE at 12 months (at the end of therapy)
The Mini-International Neuropsychiatric Interview (MINI)
Treatment related variable (moderator)
Time frame: Change from baseline in MINI at 12 months (at the end of therapy)
Youth Psychopathy Traits Inventory (YPI)
Treatment related variable (moderator)
Time frame: only baseline assessment
Cultural-Fair-Test (CFT-2)
Treatment related variable (moderator)
Time frame: only baseline assessment
Childhood Experience of Care and Abuse Questionnaire (CECA-Q)
Treatment related variable (moderator)
Time frame: only baseline assessment
Dimensional Assessment of Personality Pathology - Basic Questionnaire (DAPP-BQ)
Treatment related variable (moderator)
Time frame: only baseline assessment
Plan to share: No
This study is completed, as verified in May 2022. You cannot join it, but the record below documents what was studied.
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