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Status unknownNCT02982135Updated Dec 5, 2016

Direct Bypass Versus Indirect Bypass in Treatment of Adults Hemorrhagic Moyamoya Disease

An interventional study of bypass surgery and indrect bypass surgery in Moyamoya Disease, sponsored by liuxingju. Status unknown at 1 site in China. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2016-12-05.

Sponsored by liuxingju · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Nov 2016), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
300
Allocation
Non-randomized
Ages
18 Years to 60 Years
Sex
All
01

Study summary

The investigators conducted a prospective multi-center study assessing the effect of direct bypass and indrect bypass in treatment of hemorrhagic moyamoya disease.

02

Conditions studied

  • Moyamoya Disease

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Keywords

  • hemorrhagic moyamoya disease
  • bypass
  • indirect bypass
03

In context

Moyamoya Disease

60 studies on the registry are indexed under Moyamoya Disease; 25 are open to participants now.

This study's planned enrollment of 300 is above the median of 60 across 30 interventional studies indexed under Moyamoya Disease.

Browse Moyamoya Disease studies →

Lead sponsor

liuxingju is the lead sponsor of 3 studies on the registry; none are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 60 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  1. cerebral digital subtraction contrast angiography (DSA) revealed severe stenosis or occlusion of the distal internal carotid or proximal middle and anterior cerebral arteries with prominent lenticulostriate "moyamoya collaterals"
  2. patients had experienced at least one intracranial hemorrhage which was verified by computed tomography (CT) scanning, magnetic resonance imaging MRI), or lumbar puncture.
  3. Patients requiring surgery

Exclusion criteria

Exclusion Criteria:

  1. Patient whose initial onset was marked by ischemia but subsequently suffered from intracranial hemorrhage
  2. patients refused to participate in the study
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Factorial assignment
Masking
Single (Outcomes assessor)
Enrollment
300 participants (estimated)

Study arms

  • Other
    group 1 direct bypass

    direct bypass : patients recieve direct bypass treatment

    Other: bypass surgery and indrect bypass surgery

  • Other
    group 2 indirect bypass

    indirect bypass: patients recieve indirect bypass treatment

    Other: bypass surgery and indrect bypass surgery

Interventions

  • Otherbypass surgery and indrect bypass surgery

    bypass surgery ： patients recieved STA-MCA bypass indrect bypass surgery：patients recieved EDAS or mutiple bur holes

06

What researchers measure

Primary outcomes

  1. rebleeding events

    Time frame: 5-10 years

Secondary outcomes

  1. ischemic events

    Time frame: 5-10 years

  2. postoperative compilications

    Time frame: 30 days

07

Study locations

1 of 1 sites recruiting
  • Beijing Tiantan Hospital Capital Medical University
    Beijing, Beijing 0086, China
    Recruiting
08

References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Dec 5, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02982135
Lead sponsor
liuxingju
Responsible party
liuxingju (Principal investigator, Ministry of Science and Technology of the People´s Republic of China) — Sponsor-investigator
First posted
Dec 5, 2016
Start date
Jan 2016
Primary completion
Dec 2017 (estimated)
Completion
Jan 2018 (estimated)
Last update
Dec 5, 2016

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Nov 2016. You cannot join it, but the record below documents what was studied.

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Discussion

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