An observational study in Tuberculosis, Diagnostic Techniques and Procedures and Sensitivity and Specificity, sponsored by Lille Catholic University. Completed. Per ClinicalTrials.gov, last updated 2019-03-20.
Sponsored by Lille Catholic University · Observational
Tuberculosis (TB) remains a major public health problem nowadays. About 30% of the world population is infected with Mycobacterium tuberculosis. There is an increase in the number of cases of classic tuberculosis in developing countries, even if number of cases are declining in developed countries. However, in developed countries this decrease is counterbalanced by the emergence of multidrug resistant (MDR) strains of the bacteria.
There are also latent forms (1/3 of the world population) of the infection that can be reactivated in one case out of ten. Each year, about 2 million people die of tuberculosis and 9 million new cases are identified, including about 500,000 cases of MDR TB.
The spread of this disease as well as the increasing number of cases of MDR tuberculosis, reinforce the need for research and development of strategies of diagnosis and management of this affection.
Nowadays, the culture is the gold standard for the TB diagnosis but this technique needs at least three weeks to be performed. The objective of this study is to evaluate the sensitivity and specificity of histopathological and molecular techniques (PCR) on paraformaldehyde fixed and embedded in paraffin tissues for a faster diagnosis of tuberculosis in current practice, in order to administrate an efficient treatment as soon as possible.
1,417 studies on the registry are indexed under Tuberculosis; 208 are open to participants now.
This study's enrollment of 20 is below the median of 250 across 421 observational studies indexed under Tuberculosis.
Browse Tuberculosis studies →Lille Catholic University is the lead sponsor of 111 studies on the registry; 26 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Patients with a clinical diagnosis of TB. Retrospective study on biopsy samples
Exclusion Criteria:
Patients with a clinical diagnosis of TB. Retrospective study on biopsy samples
Other: Histopathological study · Other: Molecular study (Polymerase chain reaction)
Number of positive TB cases with different techniques
Time frame: at inclusion
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Mar 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Lille Catholic University