An interventional study of Bipolife® group in Bipolar Disorders and Euthymic Status, sponsored by University Hospital, Montpellier. Terminated at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-05-14.
Sponsored by University Hospital, Montpellier · Not applicable, Interventional, and Treatment
Bipolar disorder is a condition characterized by succession of episodes- manic, hypomanic, and depressive episodes. Major risks factors of relapses are poor compliance, sleep disorder, and toxics consumption. The aims of psychoeducation programs are to increase compliance and knowledge about bipolar disorder. Serious game are supposed, in bipolar disorder, to strengthen the efficacy of psychoeducation programs. Bipolife® is a serious game which purpose is to help bipolar patients to deal with their conditions, through 3 mains messages : to pursue the treatment, to have daily routine and to request the psychiatrist in case of relapse.
This is a multicentric randomized controlled study with two harms parallels. After a classic psychoeducation group program, patients are randomized in two groups : interventional group and control group with treatment as usual.
The main objective is to evaluate the observance in the two groups. The other objectives are to evaluate daily routine, global functioning, and access to health care. Evaluations are realized at one and four months after inclusion visit. Acceptability and satisfaction about the serious game Bipolife® will be assessed in the interventional group.
Bipolife® is a serious game for bipolar patients, developed by Astra Zeneca laboratory in collaboration with a french company named Ubisoft. The aim of this interactive tool is to help patient to have a better understanding of their condition and to identify their daily routine which can impact on it.
Three visits :
At the inclusion visit (V0), on the 15days following the end of the psychoeducation group, the investigator evaluate mood, habits, daily routine, and verify inclusion criteria of the participants, in particular euthymic status. The participants are randomized by bloc in each center, in two groups : interventional group (Bipolife®) and control group.
Instructions on interventional group are to periodically connect to BIPOLIFE until next visit.
On the first visit, one month later (V1) and on the second visit, four months later (V2), the investigator evaluate compliance, routine habits and mood.
1,601 studies on the registry are indexed under Bipolar Disorder; 254 are open to participants now.
This study's enrollment of 42 is below the median of 64 across 1,223 interventional studies indexed under Bipolar Disorder.
Browse Bipolar Disorder studies →University Hospital, Montpellier is the lead sponsor of 1,244 studies on the registry; 225 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion criteria:
Bipolife group
Behavioral: Bipolife® group
No specific intervention, treatment as usual
The participant is proposed to play to the serious game Bipolife® with following instructions : * At least one connection per week during 4 weeks * Connection time is free On add on of usual treatment After the 4 weeks and the first visit (V1), the participant can continue to participate to the serious game as much as he wishes, without any specific instructions. After connecting to the site www.bipolar.ubi.com, the participant is proposed to create his avatar and conduct him on his house. He realizes different kind of daily actions (like sleeping, sport activity, cooking) ; every action lead to win or to loose "energy" and "mood" points. The final aim is to stabilize the avatar's mood. Thanks to this experience, the participant can learn to distinguish positive and negative actions impacting on his condition.
Compliance rate
Evaluation of patient compliance by Medication Adherence Rating Scale (MARS) score.
Time frame: At 4 months after the inclusion
Evolution of toxic consumption
evaluation of toxic consumption : patient will be asked about his consumption, and to pass the french scale Cut-down, Annoyed, Guilty, Eye-opener (CAGE- DETA)
Time frame: Between 1 and 4 months after the inclusion
Evolution of sleep disturbance
evaluation of sleep disturbance (by Pittsburgh Sleep Quality Index PSQI)
Time frame: Between 1 and 4 months after the inclusion
Evolution of the alimentation
evaluation of alimentation (patient will be asked about his alimentation)
Time frame: Between 1 and 4 months after the inclusion
Global functioning
evaluation of global functioning is realized by the Functioning Assessment Short Test (FAST) scale.
Time frame: At 1 and 4 months after the inclusion
Ability to access health care in emergency description : number of emergency consultation for psychiatric reason
evaluation of the ability to require to health care structures : Patients will be asked about their consultations and hospitalisations during the follow-up
Time frame: At 1 and 4 months after the inclusion
acceptability and satisfaction
only on the "interventional group" : evaluation of the acceptability and satisfaction by a home made acceptability scale.
Time frame: At 1 and 4 months after the inclusion
This study is terminated, as verified in Aug 2022. You cannot join it, but the record below documents what was studied.
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University Hospital, Montpellier