An interventional study of Personalized titanium plate in Bone Tumors, sponsored by Guangzhou General Hospital of Guangzhou Military Command. Completed. Open to participants aged 5 Years to 80 Years. Per ClinicalTrials.gov, last updated 2017-02-13.
Sponsored by Guangzhou General Hospital of Guangzhou Military Command · Not applicable, Interventional, and Treatment
Microwave ablation of bone tumors is time-consuming and usually results in postoperative fractures. Hence the investigators designed and fabricated a titanium plate customized to the patient's bone structures for fixation after the removal of tumorous tissue, to improve the clinical outcomes of microwave ablation.
3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the model of personalized titanium plates. The model of the plates was transferred into a numerical control machine for manufacturing the personalized titanium plates by 3D printing technology. The plates were then surgically implanted for reconstruction assistance following microwave-induced hyperthermia to remove the bone tumor. Implementation parameters and knee function were then evaluated.
322 studies on the registry are indexed under Bone Neoplasms; 81 are open to participants now.
This study's enrollment of 12 is below the median of 50 across 218 interventional studies indexed under Bone Neoplasms.
Browse Bone Neoplasms studies →Guangzhou General Hospital of Guangzhou Military Command is the lead sponsor of 46 studies on the registry; 1 is open to participants now.
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Exclusion Criteria:
Ten males and two females with a mean age of 22.8 years were recruited. They all had bone tumor around the knee.
Procedure: Personalized titanium plate
3D models of tumor-bearing bone segments were constructed by using computed tomography (CT) and magnetic resonance imaging (MRI). The 3D models were used to design the model of personalized titanium plates. The model of the plates was transferred into a numerical control machine for manufacturing the personalized titanium plates by 3D printing technology. The plates were then surgically implanted for reconstruction assistance following microwave-induced hyperthermia to remove the bone tumor. Implementation parameters and knee function were then evaluated.
Musculoskeletal Tumor Society score
Time frame: An average of 29 months
Mean maximum flexion of the knee
Time frame: An average of 29 months
The six degrees of freedom of the gait
including flexion/extension, adduction/abduction, internal/external rotation, anteroposterior translation, distal/lateral translation, medial/lateral translation
Time frame: An average of 29 months
Mean operation time
Time frame: Time when the operation was begun
No study locations are listed for this record.
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Feb 2017. You cannot join it, but the record below documents what was studied.
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Guangzhou General Hospital of Guangzhou Military Command