An observational study in Cerebral Artery Occlusion, sponsored by Nantes University Hospital. Completed at 1 site in France. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-06-24.
Sponsored by Nantes University Hospital · Observational
The Ischemic Brain Vascular Accident (CVA) is a major public health issue. An Early and appropriate charging anyone with stroke is essential to reduce mortality, reduce dependency and promote recovery of autonomy. Intravenous fibrinolysis in patients with cerebral infarction (NINDS 1995), is reserved for a small proportion of highly selected patients. It therefore remains a significant therapeutic challenge, especially for patients with against-indications to fibrinolysis or in whom there is no immediate benefit. For twenty years of mechanical devices have been developed to remove, as quickly as possible, the cause of intracranial arterial occlusion and allow restoration of blood flow before brain damage is irreversible.
NTF The protocol is part of the evaluation process of our clinical practices recommended by the National Health Authority (HAS), in the specific context of mechanical thrombectomy performed in French centers of interventional neuroradiology working with neurovascular units (A V).
Nantes University Hospital is the lead sponsor of 825 studies on the registry; 195 are open to participants now.
Counted across the registry records on this site, refreshed daily.
200 consecutive patients admitted to a stroke unit for cerebral infarction treated by thrombectomy included (with or without fibrinolysis by intra venous) prospectively over a period of 1 year and 3 months followed for clinical neurological assessment (primary endpoint) .
Exclusion Criteria:
clinical score for handicap (mRS)
Time frame: at 3 months
hemorrhagic complications on postoperative imaging
Time frame: baseline
hemorrhagic complications on postoperative imaging
Time frame: at 1 day
physiological parameter : age
Factors of good clinical prognosis
Time frame: baseline
presence of coronary artery disease
Factors of good clinical prognosis
Time frame: baseline
presence of arterial hypertension
Factors of good clinical prognosis
Time frame: baseline
presence of diabetes
Factors of good clinical prognosis
Time frame: baseline
presence of hypercholesterolemia
Factors of good clinical prognosis
Time frame: baseline
presence of intracranial stenosis
Factors of good clinical prognosis
Time frame: baseline
presence of occlusive arterial disease
Factors of good clinical prognosis
Time frame: baseline
presence of haematological disorders
Factors of good clinical prognosis
Time frame: baseline
presence of neoplasia
Factors of good clinical prognosis
Time frame: baseline
NIHSS score
Factors of good clinical prognosis
Time frame: baseline
ASPECTS score
Factors of good clinical prognosis
Time frame: baseline
MRI imaging of stroke
Factors of good clinical prognosis
Time frame: baseline
unblocking rate based on the score TICI
Time frame: at 3 months
NIHSS evaluation
Time frame: at 24h
Influence of collaterality score on the NIHSS
Time frame: at 24h
Influence ASPECTS score on the NIHSS
Time frame: at 24h
Influence ASPECTS score on the NIHSS
Time frame: at 3months
influence of anesthesia on the NIHSS
Time frame: at 24h
hemorrhagic complications
Time frame: at 24h
Influence of hemorrhagic complications on NIHSS
Time frame: at 24h
Influence of hemorrhagic complications on NIHSS
Time frame: at 3 months
Plan to share: Undecided
No publications or documents are linked to this record.
This study is completed, as verified in Aug 2016. You cannot join it, but the record below documents what was studied.
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Nantes University Hospital