An observational study in Acute Myocardial Infarction, sponsored by Medical University of Graz. Completed at 1 site in Austria. Open to participants aged 18 Years to 99 Years. Per ClinicalTrials.gov, last updated 2017-08-25.
Sponsored by Medical University of Graz · Observational
Besides classical cardiovascular risk factors such as smoking, obesity, elevated cholesterol levels and diabetes there are also acute factors potentially triggering acute coronary events. The impact of various substances and air pollution are described.
Particulate matter, especially with small particle size (\<2.5µm) has been shown to have a positive correlation with myocardial infarctions. However, other studies failed to show this correlation.
With respect to nitric oxydes the majority of published studies detected a significant correlation with myocardial infarction, too, although a highly ranked publication failed to show the same result. In addition data on the impact of sulfur dioxide and carbon monoxide concentration on cardiac events is very heterogeneous.
Published data indicates additive effects of age and other epidemiological variables suggesting the need of a multivariate analysis.
The rationale of the study is to test if the above mentioned air pollution factors have a significant and independent impact on the incidence of myocardial infarctions
The analysis will be performed in a well characterized patient cohort of 12.000 myocardial infarctions within 10 years being invasively diagnosed at the catheterisation centers of the styrian capital Graz.
2,744 studies on the registry are indexed under Myocardial Infarction; 418 are open to participants now.
This study's planned enrollment of 12,000 is above the median of 500 across 983 observational studies indexed under Myocardial Infarction.
Browse Myocardial Infarction studies →Medical University of Graz is the lead sponsor of 459 studies on the registry; 98 are open to participants now.
Counted across the registry records on this site, refreshed daily.
All patients with myocardial infarction being transfered to a cath lab either at the medical university of Graz or the department of cardiology at the state hospital Graz West
Exclusion Criteria:
impact of various pollution agents above threshold and their correlation with acute myocardial infarctions are analyzed
myocardial infarction
the number of myocardial infarctions of every day analysed in this study will be correlated with the respective values of air polluting substances
Time frame: 1 day
Plan to share: Undecided
This study is completed, as verified in Aug 2017. You cannot join it, but the record below documents what was studied.
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Medical University of Graz