An interventional study of Measurement of PTPdi and TTV at 4ml/kg in Congenital Diaphragmatic Hernia, sponsored by King's College London. Status unknown at 1 site in United Kingdom. Open to participants aged Up to 6 Months. Per ClinicalTrials.gov, last updated 2018-08-29.
Sponsored by King's College London · Not applicable, Interventional, and Treatment
To determine the appropriate volume (size) of ventilator breath during volume-targetted ventilation for infants born with congenital diaphragmatic hernia.
93 studies on the registry are indexed under Hernias, Diaphragmatic, Congenital; 39 are open to participants now.
This study's planned enrollment of 18 is below the median of 28 across 64 interventional studies indexed under Hernias, Diaphragmatic, Congenital.
Browse Hernias, Diaphragmatic, Congenital studies →King's College London is the lead sponsor of 506 studies on the registry; 125 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Randomised to receive TTV at 4ml/kg, 5ml/kg, 6ml/kg. Measurement of PTPdi
Device: Measurement of PTPdi · Device: TTV at 4ml/kg · Device: TTV at 5ml/kg · Device: TTV at 6ml/kg
Randomised to receive TTV at 4ml/kg, 6ml/kg, 5ml/kg. Measurement of PTPdi
Device: Measurement of PTPdi · Device: TTV at 4ml/kg · Device: TTV at 5ml/kg · Device: TTV at 6ml/kg
Randomised to receive TTV at 5ml/kg, 4ml/kg, 6ml/kg. Measurement of PTPdi
Device: Measurement of PTPdi · Device: TTV at 4ml/kg · Device: TTV at 5ml/kg · Device: TTV at 6ml/kg
Randomised to receive TTV at 5ml/kg, 6ml/kg,4ml/kg. Measurement of PTPdi
Device: Measurement of PTPdi · Device: TTV at 4ml/kg · Device: TTV at 5ml/kg · Device: TTV at 6ml/kg
Randomised to receive TTV at 6ml/kg, 5ml/kg, 4ml/kg. Measurement of PTPdi
Device: Measurement of PTPdi · Device: TTV at 4ml/kg · Device: TTV at 5ml/kg · Device: TTV at 6ml/kg
Randomised to receive TTV at 6ml/kg, 4ml/kg, 5ml/kg. Measurement of PTPdi
Device: Measurement of PTPdi · Device: TTV at 4ml/kg · Device: TTV at 5ml/kg · Device: TTV at 6ml/kg
Insertion of pressure transducer catheter to measure gastic and oesophadgeal pressures for calculation of PTPdi
Provision of targetted tidal volume of 4ml/kg
Provision of targetted tidal volume of 5ml/kg
Provision of targetted tidal volume of 6ml/kg
Change in Pressure Time Product of the diaphragm (PTPdi) at different levels of targetted tidal volume
PTPdi will be measured at each level of tidal volume. The outcome measure is the change in PTPdi.
Time frame: 3 hours
Plan to share: Undecided
No publications or documents are linked to this record.
This study is status unknown, as verified in Aug 2018. You cannot join it, but the record below documents what was studied.
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Hernias, Diaphragmatic, Congenital→
King's College London