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CompletedNCT02831322Updated Feb 15, 2023

A Study of Structure and Function of Radial Artery After Transradial Coronary Intervention

An interventional study of Percutaneous coronary intervention in Intervention and Transradial, sponsored by The First Hospital of Qinhuangdao. Completed at 1 site in China. Open to participants aged 18 Years to 80 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-02-15.

Sponsored by The First Hospital of Qinhuangdao · Not applicable, Interventional, and Prevention

Phase
Not applicable
Study type
Interventional
Enrollment
600
Allocation
Non-randomized
Ages
18 Years to 80 Years
Sex
All
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Study summary

Several approaches have been proposed to reduce the risk of RAO, including anticoagulation, immediate postprocedural sheath removal, and a small sheath/radial artery ratio. Doppler ultrasound examination showed that interrupted blood flow in RA tend to occur in the proximal end rather than distal part of the artery,which was ignored by a majority of interventional cardiologists. Different insights into occlusion location may lead to different options of sheath materials, models, catheters and puncture access. Thus, the investigators designed this present study to explore the reason of radial artery endothelial dysfuction and damage and occlusion location by flow-mediated dilation (FMD) to determine the suitable method to reduce occlusion risk during TRI.

02

Conditions studied

  • Intervention
  • Transradial

Keywords

  • Transradial
  • flow-mediated vasodilation
03

In context

Lead sponsor

The First Hospital of Qinhuangdao is the lead sponsor of 22 studies on the registry; 1 is open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 80 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • admitted for transradial catheterization.

Exclusion criteria

Exclusion Criteria:

  • femoral access, arterial circulatory disease, pathological Allen tests, decompensated heart failure, chronic renal failure
05

Study design

Phase
Not applicable
Primary purpose
Prevention
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
Single (Investigator)
Enrollment
600 participants (actual)

Study arms

  • Experimental
    radial artery occlusion

    Radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination.

    Procedure: Percutaneous coronary intervention

  • Other
    radial artery normal

    Radial artery normal was blood flow signal by Doppler ultrasound

    Procedure: Percutaneous coronary intervention

Interventions

  • ProcedurePercutaneous coronary intervention

    Percutaneous coronary intervention was a nonsurgical technique for treating obstructive coronary artery disease

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What researchers measure

Primary outcomes

  1. radial artery occlusion

    radial artery occlusion was the absence of a flow signal by Doppler ultrasound examination

    Time frame: 6 month

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Study locations

1 site
  • Qingsheng wang
    Qinhuangdao, Hebei 066000, China
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References and documents

Individual participant data

Plan to share: Yes

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 15, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02831322
Lead sponsor
The First Hospital of Qinhuangdao
Responsible party
Sponsor
First posted
Jul 13, 2016
Start date
Jul 10, 2016
Primary completion
Sep 5, 2016
Completion
Oct 1, 2017
Last update
Feb 15, 2023

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Feb 2023. You cannot join it, but the record below documents what was studied.

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