An interventional study of Intercostal plane block of the external oblique muscle in Nerve Block and Pain, sponsored by The First Hospital of Qinhuangdao. Completed at 1 site in China. Open to participants aged 18 Years to 60 Years. Per ClinicalTrials.gov, last updated 2024-11-12.
Sponsored by The First Hospital of Qinhuangdao · Not applicable, Interventional, and Prevention
Among 244 studies in Pain with a site in China — 64 open to participants now, 70 under way, 2 of them phase 3. Pain · China.
Among the 244 studies in Pain with a site in China, this one is the 154th largest by enrollment of the 209 interventional ones, is one of 25 that started in 2023, is one of 114 with no phase, and was the 174th registered.
10,054 studies on the registry are indexed under Pain; 1,649 are open to participants now.
This study's enrollment of 60 is close to the median of 66 across 8,493 interventional studies indexed under Pain.
Browse Pain studies →64 of the 244 studies in Pain with a site in China are open now, in 1 country. Each count lists the studies.
Of the 929 Pain studies recruiting now, 384 (41%) set no upper age limit and 434 (47%) stop at 75 or younger; 146 take children under 18; 222 take healthy volunteers.
This study: 18 Years to 60 Years · all sexes · no healthy volunteers.
The full table on the hub →244 studies; the count open now beside each. This study's row is marked.
First in 1992; this study’s year is marked. 25 started in 2023.
Median enrollment 120 across the 209 interventional studies, 169 across the 34 observational. Of the 121 that completed or were terminated, 17 (14%) have results posted.
50 of 244 have an industry lead sponsor. The 10 most frequent:
The First Hospital of Qinhuangdao is the lead sponsor of 22 studies on the registry; 1 is open to participants now.
The First Hospital of Qinhuangdao has 1 study filed under Pain — fewer than ten, so there is no comparison to draw.
30 of the studies in Pain with a site in China that are under way reach primary completion within a year, 1 of them phase 3. Phase 3 first, then by date:
| Study | Primary completion |
|---|---|
| NCT07872826Phase 3The Third Xiangya Hospital of Central South UniversityA Clinical Trial Evaluating the Efficacy and Safety of Local Infiltration of RF16001 for Injection for Analgesia After Total Hip Arthroplasty in China | 2027-06-30 |
| NCT07212127First Affiliated Hospital of the Chinese People's Liberation Army Naval Medical UniversityAnalgesic Effect of TENS-WAA Combined With Tramadol Hydrochloride During Oocyte Retrieval Surgery | 2026-11-08 |
| NCT07533786Haisco Pharmaceutical Group Co., Ltd.A Clinical Trial Evaluating the Efficacy and Safety of HSK55718 in Patients for Postoperative Pain Treatment in Abdominal Surgery | 2026-11-22 |
| NCT06553495Jie ChenA Comparative Analysis of Intertransverse Nerve Block and Paravertebral Nerve Block in Endoscopic Hepatectomy | 2026-11-30 |
| NCT07557823Second Affiliated Hospital, School of Medicine, Zhejiang UniversityTranscutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy | 2026-12-30 |
Among the 244 studies in Pain with a site in China, from their registry updates:
This study intends to apply external oblique intercostal muscle plane block in thoracoabdominal resection, and to explore its effect on perioperative analgesia and rehabilitation quality in patients undergoing thoracoabdominal surgery.
Approved by the hospital ethics committee, 60 patients undergoing thoracic and abdominal surgery were selected in this study. They were divided into experimental group (n=30) and control group (n=30). The experimental group was given 0.5% ropivacaine intercostal nerve block, 2.0ug/kg sufentanil and tropisetron 5mg intravenous analgesia, and the control group was given 2.0ug/kg sufentanil and tropisetron 5mg intravenous analgesia. MAP, HR and SPO2 were recorded at admission (T0), completion of induction (T1), skin incision (T2), 30min after operation (T3) and 30min after extubation (T5). The block range of nerve block in the experimental group was recorded. The VAS score and the number of patient-controlled analgesia pump were recorded 30min after extubation, 6h, 24h and 48h after operation in resting state and cough state. Postoperative adverse reactions such as respiratory depression, expectoration weakness, nausea, vomiting, and skin itching were recorded. The first time to get out of bed after operation was recorded.
Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.
Exclusion Criteria:
Given 0.5% ropivacaine intercostal nerve block, 2.0ug/kg sufentanil + tropisetron 5mg intravenous analgesia.
Procedure: Intercostal plane block of the external oblique muscle
Given intravenous analgesia with 2.0ug/kg sufentanil + tropisetron 5 mg.
Under ultrasound guidance, a single dose of 0.25% ropivacaine 20ml was given for bilateral intercostal muscle plane block of external oblique muscles
Patient's postoperative pain score
Using the VIsual Analogue Scale,patients were guided to indicate the corresponding pain score according to their own pain situation, and the score ranged from 0 to 10. To evaluate the degree of postoperative pain, a score of 0 indicates no pain at all, a score of 2 indicates mild pain, and a score of 10 indicates the most severe pain, with higher scores indicating more severe pain
Time frame: Extubation for 30minutes, 6 hours after surgery, 24 hours after surgery, and 48 hours after surgery
Changes in blood pressure
Mean arterial pressure at different time points.Mean arterial pressure will be reported in mmHg.
Time frame: Perioperative period
Changes in heart rate
Heart rate at different time points.Heart rate will be reported in counts per minute.
Time frame: Perioperative period
Extent of action of external oblique intercostal muscle plane block
The specific extent of action of the external oblique muscle intercostal muscle plane block in the thoracoabdominal wall.
Time frame: Ten minutes after the nerve block
Ran from Mar 2023 to primary completion in Jan 2024, 10 months.
Of 3,731 non-industry interventional studies with no phase under Pain, half reached primary completion within 10 months of starting (the median), counting those still running; a quarter within 4 and three quarters within 23. This study's 10 months is close to that.
Counting every sponsor, half of 3,830 studies reached it within 10 months; a quarter within 4 and three quarters within 23.
How these figures are worked out, and which studies are left out of them.
This study is completed, as verified in Nov 2024. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
The First Hospital of Qinhuangdao