Study at the Man of the Profile of Chimiokines in the Anorexia Bound to the Cancerous Cachexy

Group 1 {cancer of the pancreas WITH syndrome of anorexia-cachexie}

Inclusion Criteria:

• Patient to hospitalize in the unit of digestive cancer research.
• Patient ≥ 18 years.
• Patient carrier of an adénocarcinome of the pancreas of novo, any stadium confused, diagnosed by imaging and/or histology.
• Existence of at least one of the criteria following to hold(retain) the diagnosis of cachexie cancer patient: not deliberate loss of weight > in 5 % over the last 6 months OR(WHERE) IMC(CEREBRAL-MOTOR HANDICAPPED) \< 20 kg / m ² with a loss of minimum weight > 2 % OR(WHERE) scrawny muscular index appendiculaire respectively \< 7,26 kg / m ² at the man and \< 5,45 kg / m ² at the woman with a minimal weight loss > 2 %.
• Patient having signed the enlightened consent.

Exclusion Criteria:

• Patient having a tumor other one than the pancreatic adénocarcinome.
• Patient having a second offense of adénocarcinome pancreatic.
• Patient carrier of a pancreatic adénocarcinome in the course of a treatment by chemotherapy.
• Patient having a severe psychiatric comorbidity except TCA who can be responsible for food disorders.
• Patient carrier of an evolutionary inflammatory disease other one than the cancer being able to interfere on the inflammatory status.

Groupe 2 {cancer du pancréas SANS syndrome d'anorexie-cachexie}

Inclusion Criteria:

• Patient to hospitalize in the(unit) of digestive cancer research.
• Patient ≥ 18 years.
• Patient carrier of an adénocarcinome of the pancreas of novo, any stadium confused, diagnosed by imaging and/or histology.
• Patient having signed a enlightened consent.

Exclusion Criteria:

• Patient having a tumor other one than the pancreatic adénocarcinome.
• Patient having a second offense(recurrence) of adénocarcinome pancreatic.
• Patient carrier of a pancreatic adénocarcinome in the course of a treatment by chemotherapy.
• Existence of at least one of the criteria in favour of the diagnosis of cachexie cancer patient: not deliberate loss of weight > in 5 % over the last 6 months OR(WHERE) IMC(CEREBRAL-MOTOR HANDICAPPED) \< 20 kg / m ² with a loss of minimum weight > 2 % OR(WHERE) scrawny muscular index appendiculaire respectively \< 7,26 kg / m ² at the man and \< 5,45 kg / m ² at the woman with a minimal weight loss > 2 %.
• Patient having a severe psychiatric comorbidity except TCA who can be responsible for food disorders.
• Patient carrier of an evolutionary inflammatory disease other one than the cancer being able to interfere on the inflammatory status.
• Patient refusing to participate in the study
• Under guardianship patient or guardianship.

Group 3 {pure food limitation typifies restrictive anorexia nervosa}

Inclusion Criteria:

• Patient seen in consultation in the unit of nutritional support(medium)
• Patient ≥ 18 years.
• Patient carrier of an eating disorder of type pure restrictive anorexia nervosa (according to criterion diagnosis of the WHO)
• Patient having signed a enlightened consent.

Exclusion Criteria:

• Patient having any evolutionary organic pathology source of a decrease of the oral contributions and/or the interference on the inflammatory status, and responsible for a loss of weight
• Patient refusing to participate in the study
• Under guardianship patient or guardianship.

Group 4 {unhurt individual of any appetite-suppressing evolutionary disease and cachectisante}

Inclusion Criteria:

• Patient seen in consultation of hepatogastroenterology
• Patient ≥ 18 years.
• Unhurt patient of any organic or psychic, evolutionary pathology, cachectisante
• Patient having signed a enlightened consent.

Exclusion Criteria:

• Patient refusing to participate in the study
• Under guardianship patient or guardianship.