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WithdrawnNCT02828345Updated Feb 5, 2020

Bio-marker Analysis Using Circulating Tumor Cells in Patients With Melanoma

An observational study in Melanoma, sponsored by Abramson Cancer Center at Penn Medicine. Withdrawn. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2020-02-05.

Sponsored by Abramson Cancer Center at Penn Medicine · Observational

Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
0
Ages
18 Years and older
Sex
All
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Study summary

This research trial studies the levels of a type of biomarker, circulating tumor cells (CTCs), in the blood of patients with stage I-IV melanoma. A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Studying samples of blood in the laboratory obtained before and after treatment from patients with melanoma may help doctors learn more about changes that occur in CTC levels and whether they may predict how well patients will respond to therapy.

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Conditions studied

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In context

Melanoma

3,006 studies on the registry are indexed under Melanoma; 520 are open to participants now.

Browse Melanoma studies →

Lead sponsor

Abramson Cancer Center at Penn Medicine is the lead sponsor of 446 studies on the registry; 86 are open to participants now.

Of its 32 completed or terminated interventional studies of FDA-regulated products, 14 (44%) have results posted.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Probability sample

Study population

Melanoma

Inclusion criteria

  • Subjects must have signed tissue collection consent as described in protocol IRB# 703001,UPCC# 08607, PI: Giorgos Karakousis, MD
  • Subjects must be competent to consent for themselves.
  • Subjectsmust be adult (18 years or older).
  • Subjects must be initiating a new therapy for melanoma (so a pretreatment CTC count can be obtained).

Exclusion criteria

Exclusion Criteria:

  • Children (less than 18yrs)
  • Patients in whom a pre-treatment CTC level cannot be obtained.
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Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
0 participants (actual)
Patient registry
No

Interventions

  • OtherSpecimen Collection
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What researchers measure

Primary outcomes

  1. Number of changes in CTC level from pre- to post-treatment

    Time frame: two years

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Study locations

No study locations are listed for this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Feb 5, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02828345
Lead sponsor
Abramson Cancer Center at Penn Medicine
Responsible party
Sponsor
First posted
Jul 11, 2016
Start date
Nov 2013
Primary completion
Dec 2013
Completion
Dec 2013
Last update
Feb 5, 2020

Study contacts

Giorgos Karakousis, MD
principal investigator · Abramson Cancer Center at Penn Medicine

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is withdrawn, as verified in Jan 2020. You cannot join it, but the record below documents what was studied.

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