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CompletedNCT02826746Updated Apr 5, 2019

Effect of Intravenous Magnesium on Postoperative Sore Throat After Thyroidectomy

An interventional study of Magnesium Sulfate and Normal saline in Thyroid Neoplasms, sponsored by Ajou University School of Medicine. Completed at 1 site in Korea, Republic of. Open to female participants aged 20 Years to 85 Years. Per ClinicalTrials.gov, last updated 2019-04-05.

Sponsored by Ajou University School of Medicine · Not applicable, Interventional, and Treatment

Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Randomized
Ages
20 Years to 85 Years
Sex
Female
01

Study summary

The primary purpose of this study is to investigate the effect of intravenous magnesium on postoperative throat pain after thyroidectomy.

The secondary purpose of this study is to investigate the effect of intravenous magnesium on total dose of fentanyl in recovery room after thyroidectomy.

02

Conditions studied

  • Thyroid Neoplasms

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03

In context

Thyroid Neoplasms

802 studies on the registry are indexed under Thyroid Neoplasms; 216 are open to participants now.

This study's enrollment of 20 is below the median of 51 across 507 interventional studies indexed under Thyroid Neoplasms.

Browse Thyroid Neoplasms studies →

Lead sponsor

Ajou University School of Medicine is the lead sponsor of 171 studies on the registry; 16 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
20 Years to 85 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Thyroidectomy

Exclusion criteria

Exclusion Criteria:

  • Allergy to magnesium
  • Chronic pain
  • Chronic opioid use
  • Chronic NSAID use
  • Renal dysfunction
  • Liver dysfunction
  • Cardiac arrythmia
  • Seizure
05

Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
20 participants (actual)

Study arms

  • Experimental
    Magnesium group

    intravenous administration of Magnesium Sulfate

    Drug: Magnesium Sulfate

  • Placebo comparator
    Control group

    intravenous administration of normal saline

    Drug: Normal saline

Interventions

  • DrugMagnesium Sulfate

    adminstration of intravenous magnesium as bolus of 50 mg/kg, followed by continuous infusion at rate of 10 mg/kg/h

  • DrugNormal saline

    the same bolus and infusion volumes of normal saline

06

What researchers measure

Primary outcomes

  1. Throat pain

    pain assessment using visual analog scale

    Time frame: Up to 48 hours after surgery end

Secondary outcomes

  1. Fentanyl dose in recovery room

    Time frame: Up to 30 minutes after surgery end

07

Study locations

1 site
  • Department of Anesthesiology and Pain Medicine, Ajou University School of Medicine
    Suwon, Seoum, Korea, Republic of
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 5, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02826746
Lead sponsor
Ajou University School of Medicine
Responsible party
Ji Eun Kim (Assistant professor, Ajou University School of Medicine) — Principal investigator
First posted
Jul 11, 2016
Start date
Jul 2016
Primary completion
Mar 2019
Completion
Mar 2019
Last update
Apr 5, 2019
View the source record on ClinicalTrials.gov ↗

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This study is completed, as verified in Apr 2019. You cannot join it, but the record below documents what was studied.

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