An interventional study of electrical stimulation in Epilepsy, sponsored by Barbara Jobst. Completed at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2025-07-30.
Sponsored by Barbara Jobst · Not applicable, Interventional, and Other
This study is designed to identify brain activity associated with good memory in subjects with a chronically implanted RNS® device and to study the effects of therapeutic stimulation for epilepsy on memory. This will be accomplished through analysis of ECoG data collected during memory encoding for short and long-term free recall as well as during navigation tasks.
1,805 studies on the registry are indexed under Epilepsy; 417 are open to participants now.
This study's enrollment of 9 is below the median of 50 across 1,206 interventional studies indexed under Epilepsy.
Browse Epilepsy studies →This is the only study on the registry with Barbara Jobst as lead sponsor.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Subjects with pharmaceutically intractable seizures who have been implanted with a RNS® Neurostimulator.
Other: electrical stimulation
Stimulation applied will be within parameters commonly used for the treatment of epilepsy during periods of encoding, recall, and memory maintenance .
Proportion of words recalled with and without stimulation.
This study is designed to study the effects of therapeutic stimulation for epilepsy on memory. This outcome will be assessed by free recall language and memory tasks.
Time frame: 30 days
Changes in the power spectrum of ECoG data with an increase of recalled words.
This study is designed to identify brain activity associated with good memory in subjects with a chronically implanted RNS® device. This outcome will be assessed by free recall language and memory tasks.
Time frame: 30 days
Proportion of words recalled during times of interictal activity.
This study is designed to investigate the effects of IEDs on spatial, long-term, and short-term memory. This will be assessed by free recall language and memory tasks.
Time frame: 30 days
Proportion of navigation challenges recalled successfully with and without stimulation.
This outcome will be assessed by real-world and virtual navigation tasks.
Time frame: 30 days
Plan to share: No
No publications or documents are linked to this record.
This study is completed, as verified in Jul 2025. You cannot join it, but the record below documents what was studied.
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