CClinicalTrials.gg
RecruitingNCT02764606CANPOSUpdated Apr 2, 2019

CANPOS: Predictive Biomarkers of Tumor Progression in Non-small Cell Lung Cancer

An observational study in Non-small Cell Lung Cancer, sponsored by Hospices Civils de Lyon. Recruiting at 1 site in France. Open to participants aged 18 Years to 70 Years. Per ClinicalTrials.gov, last updated 2019-04-02.

Sponsored by Hospices Civils de Lyon · Observational

From the registry’s dates

  • Primary completion was expected by Dec 2025, 10 months ago, but the record still lists the study as recruiting.
Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
250
Ages
18 Years to 70 Years
Sex
All
01

Study summary

CANPOS is a non-interventional study aiming at evaluate at the time of initial surgery the value of new serum markers to predict the occurrence of metastases in patients with early-stage non-small cell lung cancer. This would represent a rational to develop personalized follow-up and prevention strategies

02

Conditions studied

  • Non-small Cell Lung Cancer

Keywords

  • Lung Cancer
  • Biomarkers
  • Bone
  • Metastases
03

In context

Lung Neoplasms

7,243 studies on the registry are indexed under Lung Neoplasms; 1,557 are open to participants now.

This study's planned enrollment of 250 is above the median of 189 across 1,514 observational studies indexed under Lung Neoplasms.

Browse Lung Neoplasms studies →

Lead sponsor

Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
18 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Early-stage non-small cell lung cancer

Inclusion criteria

  • patients with a diagnosis or suspected for a diagnosis of lung cancer, non-small cell lung cancer
  • age over 18 years
  • patient naïve of any oncology treatment (excluding surgery alone) within the past 5 years
  • patient who signed the informed consent by the study protocol

Exclusion criteria

Exclusion criteria were:

  • any ongoing treatment for cancer
  • any history of cancer within 5 years before the diagnosis of lung cancer
  • any psychological, sociological or geographical conditions that would not allow the study follow-up
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
250 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna

Groups and cohorts

  • Patients with a non-small cell lung cancer

    Serum and plasma samples (at time of diagnosis, after surgery, and at time of progression to evaluate the value of new serum markers to predict the occurrence of metastases).

    Biological: Serum and plasma samples

Interventions

  • BiologicalSerum and plasma samples

    Serum and plasma are collected at time of diagnosis, after surgery, and at time of progression to evaluate the value of new serum markers to predict the occurrence of metastases.

06

What researchers measure

Primary outcomes

  1. The Serum levels of osteoprotegerin

    The serum levels of osteoprotegerin, as assessed by standard ELISA methods, will be measured to to evaluate at the time of initial surgery, the value of new serum markers to predict the occurrence of metastases in patients with early-stage non-small cell lung cancer.

    Time frame: At the time of initial surgery

07

Study locations

1 of 1 sites recruiting
  • Hospices Civils de Lyon / Hôpital Neurologique Pierre Wertheimer
    Bron, 69500, France
    Recruiting
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Apr 2, 2019, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02764606
Lead sponsor
Hospices Civils de Lyon
Responsible party
Sponsor
First posted
May 6, 2016
Start date
Nov 2013
Primary completion
Dec 2025 (estimated)
Completion
Dec 2025 (estimated)
Last update
Apr 2, 2019

Study contacts

Nicolas Girard
Contact
nicolas.girard@chu-lyon.fr
+33427857700
Cyrille Confavreux
Contact
cyrille.confavreux@chu-lyon.fr
+33472117482

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Interested in this study?

Eligibility is decided by the study team. Share this record with your doctor or contact the team directly.

Contact study team

Follow this study

Get an email when the registry record changes — status, dates, results — or when someone posts here.

Sign in to follow

Discussion

Questions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.

Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.

Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.

Start the discussion