CClinicalTrials.gg
Status unknownNCT02763657NEUREASUpdated May 5, 2016

Neural Development of Deductive Reasoning

An interventional study of fMRI scanning in Healthy Volunteers, sponsored by Hospices Civils de Lyon. Status unknown at 1 site in France. Open to participants aged 8 Years to 14 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-05-05.

Sponsored by Hospices Civils de Lyon · Not applicable, Interventional, and Basic science

The sponsor has not verified this record recently (last verified May 2016), so the status shown — last known as Recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
60
Allocation
Not applicable
Ages
8 Years to 14 Years
Sex
All
01

Study summary

Children's understanding of linear-order (e.g., Dan is taller than Lisa, Lisa is taller than Jess) and set-inclusion (i.e., All tulips are flowers, All flowers are plants) relationships is critical for the acquisition of deductive reasoning, that is, the ability to reach logically valid conclusions from given premises. Behavioral and neuroimaging studies in adults suggest processing differences between these relations: While arguments that involve linear-orders may be preferentially associated with spatial processing, arguments that involve set-inclusions may be preferentially associated with verbal processing. In this study, we use functional magnetic resonance imaging to investigate how and when these processing differences appear in children from 8 to 14.

02

Conditions studied

  • Healthy Volunteers

Keywords

  • fMRI
  • reasoning
  • development
03

In context

Lead sponsor

Hospices Civils de Lyon is the lead sponsor of 1,826 studies on the registry; 439 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
8 Years to 14 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Inclusion criteria

  • Right-handed
  • Affiliated to the French social security
  • Whose parents gave informed consent

Exclusion criteria

Exclusion Criteria:

  • Neurological disorders
  • Psychiatric disorders
  • Birth complications requiring admission into neonatal intensive care unit
  • Medication affecting central nervous system processing
  • Significant hearing impairment
  • Uncorrected visual impairment
  • Non-native English speaker
  • Contraindications for MRI
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Not applicable
Intervention model
Single group
Masking
None (open label)
Enrollment
60 participants (estimated)

Study arms

  • Experimental
    Brain activity during reasoning

    Other: fMRI scanning

Interventions

  • OtherfMRI scanning

    All participants are scanned while evaluating linear-order and set-inclusion reasoning problems

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What researchers measure

Primary outcomes

  1. Identification of brain regions engaged in linear-order and set-inclusion reasoning

    Brain activity measured using fMRI

    Time frame: 30 days

Secondary outcomes

  1. Degree of overlap between brain regions involved in linear-order and set-inclusion reasoning

    Degree of overlap in brain activity measured using fMRI

    Time frame: 30 days

07

Study locations

1 of 1 sites recruiting
  • Hospices Civils de Lyon
    Lyon/bron, 69500, France
    Recruiting
08

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 5, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT02763657
Lead sponsor
Hospices Civils de Lyon
Responsible party
Sponsor
First posted
May 5, 2016
Start date
Oct 2013
Primary completion
Dec 2016 (estimated)
Completion
Dec 2016 (estimated)
Last update
May 5, 2016

Study contacts

Christian SCHEIBER, Pr, MD
Contact
christian.scheiber@chu-lyon.fr
4 72 68 49 61 ext. +33
Justine EPINAT, CRA
Contact
jepinat@isc.cnrs.fr
4 37 91 12 64 ext. + 33

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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