CClinicalTrials.gg
Status unknownNCT02761278Updated May 12, 2016

Expression of HOXA10 and HOXA11 in the Endometrium of Infertility Patients With an Endometrial Polyp Before and After Polypectomy

An interventional study of Endometrial biopsy in Infertility, sponsored by Hillel Yaffe Medical Center. Status unknown. Open to female participants aged 20 Years to 40 Years. Per ClinicalTrials.gov, last updated 2016-05-12.

Sponsored by Hillel Yaffe Medical Center · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified May 2016), so the status shown — last known as Not yet recruiting — may be out of date.
Phase
Not applicable
Study type
Interventional
Enrollment
20
Allocation
Non-randomized
Ages
20 Years to 40 Years
Sex
Female
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Study summary

The aim of this study is to measure the expression of HOXA10 and HOXA11 in the endometrium of infertility patients with an endometrial polyp before and after polypectomy. HOXA10 and HOXA11 are well-established markers of implantation. It is uncertain as to whether an endometrial polyp interferes with embryo implantation. A higher expression of HOXA10 and HOXA11 after polypectomy can indicate that endometrial polyp does interfere with embryo implantation.

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Conditions studied

  • Infertility

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In context

Infertility

2,506 studies on the registry are indexed under Infertility; 407 are open to participants now.

This study's planned enrollment of 20 is below the median of 120 across 1,698 interventional studies indexed under Infertility.

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Lead sponsor

Hillel Yaffe Medical Center is the lead sponsor of 301 studies on the registry; 10 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
20 Years to 40 Years
Sexes eligible
Female
Accepts healthy volunteers
No

Inclusion criteria

  • Infertile women with endometrial polyp

Exclusion criteria

Exclusion Criteria:

  • Endometriosis
  • Polycystic ovary syndrome
  • Hydrosalpinx
  • Sub-mucus myoma
  • Women who have taken hormonal therapy in the preceding month
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Study design

Phase
Not applicable
Primary purpose
Treatment
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
20 participants (estimated)

Study arms

  • Active comparator
    HOXA10 and HOXA11 Expression Before Polypectomy

    A biopsy will taken in infertility patients with endometrial polyp before polypectomy

    Procedure: Endometrial biopsy

  • Active comparator
    HOXA10 and HOXA11 Expression After Polypectomy

    A biopsy will taken in infertility patients with endometrial polyp 1-3 months after polypectomy

    Procedure: Endometrial biopsy

Interventions

  • ProcedureEndometrial biopsy
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What researchers measure

Primary outcomes

  1. Comparison of amounts of HOXA10 and HOXA11 expressed before and after polypectomy

    Time frame: Four months

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Study locations

No study locations are listed for this record.

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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

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Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 12, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02761278
Lead sponsor
Hillel Yaffe Medical Center
Responsible party
Sponsor
First posted
May 4, 2016
Start date
Jul 2016
Primary completion
Jul 2017 (estimated)
Completion
Jul 2017 (estimated)
Last update
May 12, 2016

Study contacts

Guy Shrem, MD
Contact
dr.shremguy@gmail.com
Guy Shrem, MD
principal investigator · Hillel Yaffe Medical Center

Oversight

Data monitoring committee
Yes
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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