A Phase 2 interventional study of Dental restoration and 3 step ER in Dental Caries, sponsored by Universidad de Valparaiso. Status unknown at 1 site in Chile. Open to participants aged 18 Years and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2016-04-26.
Sponsored by Universidad de Valparaiso · Phase 2, Interventional, and Treatment
This study aims to evaluate the clinical effectiveness of contemporary resin-based adhesive systems by retention rate of resin restorations placed in non carious cervical lesions with four different adhesive strategies: 3 and 2 steps etch-and-rinse adhesive system, 2 and 1 step self-etch adhesive systems.
The etch-and-rinse (3 and 2 steps) and self-etch (1 and 2 steps) adhesive systems allow the bond between the resins restorations with the dental substrates, but they have mechanism of action different.
The success of resin composite restorations is reliant upon adhesion to the underlying tooth via adhesive systems. The mechanism of adhesion to enamel and dentine could be involved for one hand, the etching the substrates with 30-40% phosphoric acid, followed by the application of a primer and subsequently an adhesive resin 3 steps etch-and- rinse approach or 2 steps when to combine the primer and adhesive into one bottle. For another hand, the self- etch systems with acid monomers in their primer, allow conditioning the surface without phosphoric acid step. So, they consist of either a self-etching primer accompanied by an adhesive resin applied as a subsequent step (2 steps) or a self-etch adhesive, which does not require a separate primer (1 step).
1,109 studies on the registry are indexed under Dental Caries; 197 are open to participants now.
This study's planned enrollment of 185 is above the median of 60 across 916 interventional studies indexed under Dental Caries.
Browse Dental Caries studies →Universidad de Valparaiso is the lead sponsor of 28 studies on the registry; 4 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Dental restoration with etching the dental substrates 35% phosphoric acid, followed by the application of a primer and subsequently an adhesive resin.
Procedure: Dental restoration · Procedure: 3 step ER
Dental restoration with etching the dental substrates 35% phosphoric acid, followed by the application of an adhesive/primer step.
Procedure: Dental restoration · Procedure: 2 step ER
Dental restoration with etching the dental substrates with acidic primer, followed by the application of adhesive resin.
Procedure: Dental restoration · Procedure: 2 step SE
Dental restoration with etching and infiltrate the dental substrates with acidic primer/adhesive system.
Procedure: Dental restoration · Procedure: 1 step SE
Methacrylate resins will be used to complement the cavity restoration after of adhesive procedure
Also known as: Dental resin restoration
Enamel and dentin will be conditioning with 35% phosphoric acid, then applied primer, and then applied adhesive resin.
Enamel and dentin will be conditioning with 35% of phosphoric acid, then applied primer/adhesive resin.
Enamel and dentin will be conditioning with acidic primer, then applied primer/adhesive resin.
Enamel and dentin will be conditioning with acidic primer/adhesive resin.
Secondary caries
Secondary caries near and/or associated of the dental restorations
Time frame: one year
Retention rate
retention rate of the dental restorations
Time frame: one year
Marginal integrity
marginal integrity of the dental restorations
Time frame: one year
Marginal discoloration
Marginal discoloration of the dental restorations
Time frame: one year
post-operative sensitivity
dentin post-operative sensitivity
Time frame: one year
Plan to share: No
This study is status unknown, as verified in Apr 2016. You cannot join it, but the record below documents what was studied.
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Universidad de Valparaiso