ClinicalTrials.gg
CompletedNCT02734888Updated Oct 4, 2023

Arterial Inflammation and E-Cigarettes

An interventional study of No drug or device, only a test. The test is called a PET/CT in Arterial Inflammation, sponsored by University of California, Los Angeles. Completed at 1 site in United States. Open to participants aged 21 Years to 45 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2023-10-04.

Sponsored by University of California, Los Angeles · Not applicable, Interventional, and Diagnostic

Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Non-randomized
Ages
21 Years to 45 Years
Sex
All
01

Study summary

Arterial inflammation will be compared using PET scanning in 3 groups: 1) Non-smokers, 2) Tobacco cigarette smokers, 3) Electronic cigarette users.

Read the detailed description

Qualified participants will undergo a singe PET/CT to detect arterial inflammation.

02

Conditions studied

  • Arterial Inflammation

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Keywords

  • arterial inflammation
  • electronic cigarettes
  • PET scan
03

In context

Arteritis

20 studies on the registry are indexed under Arteritis; 3 are open to participants now.

This study's enrollment of 30 is below the median of 64 across 12 interventional studies indexed under Arteritis.

Browse Arteritis studies →

Lead sponsor

University of California, Los Angeles is the lead sponsor of 1,170 studies on the registry; 195 are open to participants now.

Of its 95 completed or terminated interventional studies of FDA-regulated products, 70 (74%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
21 Years to 45 Years
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

Healthy

  • Nonsmokers OR
  • Daily e-cigarette user OR
  • Daily tobacco cigarette smoker

Exclusion criteria

Exclusion Criteria:

  • Cardiac disease
  • Respiratory Disease
  • Diabetes mellitus
05

Study design

Phase
Not applicable
Primary purpose
Diagnostic
Allocation
Non-randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (actual)

Study arms

  • Other
    Healthy control

    Will undergo PET scan as a "negative control"

    Other: No drug or device, only a test. The test is called a PET/CT

  • Other
    Tobacco cigarette smoker

    Will undergo PET scan as a "positive control"

    Other: No drug or device, only a test. The test is called a PET/CT

  • Other
    E-cigarette user

    Will undergo PET scan

    Other: No drug or device, only a test. The test is called a PET/CT

Interventions

  • OtherNo drug or device, only a test. The test is called a PET/CT

    A single PET/CT scan will be performed

06

What researchers measure

Primary outcomes

  1. target-to-background ratio (TBR)

    TBR will be detected on the scan

    Time frame: intraoperative

07

Study locations

1 site
  • UCaliforniaLA
    Los Angeles, California 90095, United States
08

Timeline

Tracking since Sep 25, 2026
Not marked actual or estimatedDates not marked actual or estimated

The record gives a start of Jul 2015, a primary completion of Feb 2023 and a completion of Feb 2023. It does not say whether these dates are actual or estimated.

How these figures are worked out, and which studies are left out of them.

Registered
Apr 1, 2016
First posted
Apr 12, 2016
Start
Jul 2015
Primary completionActual
Feb 1, 2023
CompletionActual
Feb 1, 2023
Last update
Oct 4, 2023
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Oct 4, 2023, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT02734888
Responsible party
Holly R Middlekauff (Professor of Medicine, University of California, Los Angeles) — Principal investigator
First posted
Apr 12, 2016
Start date
Jul 2015
Primary completion
Feb 1, 2023
Completion
Feb 1, 2023
Last update
Oct 4, 2023

Study contacts

Holly R Middlekauff, MD
principal investigator · University of California, Los Angeles

Oversight

Data monitoring committee
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2023. You cannot join it, but the record below documents what was studied.

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Discussion

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