CARDIOSPACE Evaluation in Healthy Volunteers

• Age : 18 to 40 years
• Size : 160 à 180
• Weight : BMI between 18 and 24

• Medical history :

  • No history of cardiovascular disease
  • No chronic treatment
  • No syncopal events (>2 by year)

• Physical examination

  • Normal cardio-pulmonary ausculation
  • Normal (DBP [60 - 90] SBP [100 - 140]
  • Normal heart rate (between 50 and 80 at rest)

• Complementary examination

  • Normal Electrocardiogram
  • Presence of temporal acoustic window
• Capable to understand the objectives and constraints of this study
• Covered by health social insurance
• Have signed the informed consent

Exclusion Criteria:

• Pregnant woman (beta HCG by urinary test) or breastfeeding

  • Refusing to sign the informed consent
  • Don't understand the objectives of this study
  • Minors or majors protect by the law
  • Don't Benefit of social insurance
  • Participation at the time of study enrolment during the present trial period in another clinical trial investigating.
  • Having reached or surpassed the annual amount of compensation allowed by clinical trials
  • Receipt of any chronic and regular treatment
  • Presence of sign cardiovascular diseases during the questioning
  • Presence of sign cardiovascular diseases during the examination
  • Presence of sign syncopals events ATCD diseases during the questioning (>2 by year)
  • Absence of temporal acoustic window with the Transcranial Doppler
  • Respiratory disorder, asthma
  • Any troubles preventing the realization of physical activity