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CompletedNCT02690506Updated May 18, 2016

The Effect of Pregabalin on the Spinal Anesthesia

An interventional study of Placebo and Pregabalin in Block, sponsored by Kyungpook National University Hospital. Completed at 1 site in Korea, Republic of. Open to participants aged 19 Years to 70 Years. Per ClinicalTrials.gov, last updated 2016-05-18.

Sponsored by Kyungpook National University Hospital · Not applicable and Interventional

Phase
Not applicable
Study type
Interventional
Enrollment
44
Allocation
Randomized
Ages
19 Years to 70 Years
Sex
All
01

Study summary

Pregabalin, an anticonvulsant is widely used for treatment of neuropathic pain. Recently, it was reported that premedication of pregabalin before general anesthesia is effective to reduce postoperative pain. Up to date, there is no study about the effect of premedication of pregabalin on the spinal anesthesia. Therefore, in this study, investigators investigate the effect of premedication of pregabalin on the spinal anesthesia.

Read the detailed description

In this study, investigators investigate the effect of premedication of pregabaline 150 mg on the spinal anesthesia. Two hours before spinal anesthesia, placebo pill was administered to patients in the group C and pregabalin 150 mg was administered to patients in the group P, respectively. Time for the onset of blockade, cephalad level of analgesia and duration of analgesia were measured.

02

Conditions studied

  • Block

Keywords

  • pregabalin
  • spinal anesthesia
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In context

Lead sponsor

Kyungpook National University Hospital is the lead sponsor of 76 studies on the registry; 8 are open to participants now.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
19 Years to 70 Years
Sexes eligible
All
Accepts healthy volunteers
No

Inclusion criteria

  • Patients of American Society of Anaesthesiologists Grades I and II

Exclusion criteria

Exclusion Criteria:

  • Patients with infection at the puncture site, coagulopathy, having true hypersensitivity to drugs used, diabetes and hypertension, psychiatric and neurological diseases
05

Study design

Phase
Not applicable
Allocation
Randomized
Intervention model
Parallel assignment
Masking
Quadruple (Participant, Care provider, Investigator, Outcomes assessor)
Enrollment
44 participants (actual)

Study arms

  • Placebo comparator
    Group C

    Oral placebo pill was administered 2 hours before anesthesia

    Drug: Placebo

  • Active comparator
    Group P

    Oral pregabalin 150 mg was administered 2 hours before anesthesia

    Drug: Pregabalin

Interventions

  • DrugPlacebo
  • DrugPregabalin
06

What researchers measure

Primary outcomes

  1. Duration of spinal anesthesia

    Duration of spinal anesthesia was measured 24 after spinal anesthesia

    Time frame: 24 hours after spinal anesthesia

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Study locations

1 site
  • Kyungpook National University Hospital
    Daegu, 700-721, Korea, Republic of
08

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 18, 2016, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT02690506
Lead sponsor
Kyungpook National University Hospital
Responsible party
Younghoon Jeon (Professor, Kyungpook National University Hospital) — Principal investigator
First posted
Feb 24, 2016
Start date
Feb 2016
Primary completion
May 2016
Completion
May 2016
Last update
May 18, 2016

Study contacts

Younghoon Jeon, Dr
principal investigator · Kyungpook National University Hospital
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in May 2016. You cannot join it, but the record below documents what was studied.

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