An interventional study of 5% dextrose and normal saline in Delivery Uterine, sponsored by Université de Sherbrooke. Completed at 1 site in Canada. Open to female participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2016-10-31.
Sponsored by Université de Sherbrooke · Not applicable and Interventional
The objective of this study is to compare the effects of use of normal saline (250 cc / h), with or without dextrose supplement, on the evolution of labor in nulliparous.
There is some controversy regarding intravenous hydration of patients during labor. While the use of a fast flow of hydration appears to be recognized beneficial, the addition of glucose is less well accepted. However studies on exercise physiology clearly demonstrates improved performance of skeletal muscle by increased hydration and carbohydrate replacement during prolonged exercise. This situation is similar to the condition of the uterus in labor especially since it is now established that glucose represents its principal source of energy.
However, the effect of an additional carbohydrate intake on the evolution of labor has not been extensively studied until now, and there are several schools of thought on this subject. While some studies show that such glucose addition could reduce the total duration of labor as well as its second stage, others claim that this glucose supplement offers no benefit and may even be harmful to the fetus.
It therefore seems imperative to conduct a study to compare the use of hydration with normal saline with or without dextrose during labor, as recommended in current flow (250 cc / h). To our knowledge, this has never been done.
Université de Sherbrooke is the lead sponsor of 289 studies on the registry; 68 are open to participants now.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
normal saline, 250 ml/h, until expulsion of placental
Other: normal saline
normal saline + 5% dextrose, 250 ml/h, until expulsion of placental
Other: 5% dextrose · Other: normal saline
women with an elective induction of labor receive IV hydratation (250 ml/h) with a normal saline solution + 5% dextrose
women with an elective induction of labor receive IV hydratation (250 ml/h) with a normal saline solution
2nd stage of labor
Time frame: during delivery of a first baby, for an average of 5 hours
Plan to share: Yes — Oral presentation at the Society of Maternal and Fetal Medicine annual meeting (January 2017, Las Vegas) Manuscript in preparation
No publications or documents are linked to this record.
This study is completed, as verified in Oct 2016. You cannot join it, but the record below documents what was studied.
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Université de Sherbrooke