A Phase 1/2 interventional study of Carbon monoxide-bubbled mediums in Chronic Pancreatitis, sponsored by Medical University of South Carolina. Completed at 1 site in United States. Open to participants aged 18 Years to 69 Years. Per ClinicalTrials.gov, last updated 2019-01-04.
Sponsored by Medical University of South Carolina · Phase 1/2, Interventional, and Other
The goal of this study is to determine whether harvesting islets using carbon monoxide (CO)-saturated mediums can protect islet cell from death after autologous islet transplantation in patients with chronic pancreatitis.
Investigators plan to harvest human islets using carbon monoxide-saturated mediums. Survival and function of transplanted islets will be compared with islets harvested using regular mediums.
752 studies on the registry are indexed under Pancreatitis; 181 are open to participants now.
This study's enrollment of 16 is below the median of 80 across 448 interventional studies indexed under Pancreatitis.
Browse Pancreatitis studies →Medical University of South Carolina is the lead sponsor of 852 studies on the registry; 165 are open to participants now.
Of its 128 completed or terminated interventional studies of FDA-regulated products, 101 (79%) have results posted.
Counted across the registry records on this site, refreshed daily.
Exclusion Criteria:
Note: The study was initially designed only to enroll diabetes free patients. To increase enrollment, we extended the inclusion criteria by allowing patients who are pre-diabetic to participate the study. This revision was approved by the MUSC IRB on 11/10/2015.
Islets will be harvested with Carbon monoxide-saturated mediums
Other: Carbon monoxide-bubbled mediums
Islets will be harvested with regular mediums
Islets will be harvested with carbon monoxide bubbled mediums
Area under the curve during mixed meal tolerance test
Time frame: 6 months
This study is completed, as verified in Jan 2019. You cannot join it, but the record below documents what was studied.
Get an email when the registry record changes — status, dates, results — or when someone posts here.
Sign in to followQuestions and observations about this study, from anyone following it. Not medical advice, and not a channel to the study team — their contact details are on the registry record.
Sign in to join the discussion. Reading takes no account; posting does. You choose a display name, and a pseudonym is the default.
Nothing here yet. If you are running this trial, taking part in it, or weighing whether to, this is the place to say so.
Medical University of South Carolina