An observational study in Critical Illness, sponsored by Yonsei University. Completed. Per ClinicalTrials.gov, last updated 2017-08-04.
Sponsored by Yonsei University · Observational
To investigate natural killer (NK) cell activities, circulating cytokine levels and peripheral blood mononuclear cell (PBMC) cytokine production status in critically ill patients.
Blood samples were collected \< 24 hours after admission from 24 intensive care unit (ICU) patients and 24 age-, sex-, and body mass index (BMI)-matched healthy controls. NK cell activities, cytokine concentrations and cytokine production by PBMCs and lipopolysaccharide (LPS)-stimulated PBMCs were measured.
1,881 studies on the registry are indexed under Critical Illness; 462 are open to participants now.
This study's enrollment of 48 is below the median of 130 across 867 observational studies indexed under Critical Illness.
Browse Critical Illness studies →Yonsei University is the lead sponsor of 1,387 studies on the registry; 232 are open to participants now.
Counted across the registry records on this site, refreshed daily.
From April 2014 to July 2015, 24 critically ill patients were enrolled in this study after admission to the ICU at Yonsei University Severance Hospital. For validation of the experimental findings, age-, sex- and BMI-matched healthy subjects were enrolled as controls among individuals seen at a health evaluation center during the same period.
Exclusion Criteria:
Critically ill patients who were enrolled less than 24 hours after ICU admission.
Age-, sex-, and BMI-matched healthy subjects.
NK cell activity
NK cell activity (%)
Time frame: Baseline
IL (Interleukin)-12
IL-12 (pg/mL)
Time frame: Baseline
hs-CRP (high-sensitivity C-reactive protein)
hs-CRP (mg/dL)
Time frame: Baseline
No study locations are listed for this record.
This study is completed, as verified in Aug 2017. You cannot join it, but the record below documents what was studied.
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Yonsei University